Index Catalog // ScholarsArchive@OSU

Assessing mechanisms of immunotoxicity for polycyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss)

Creator:: Bravo, Claudia F.
Abstract:: During the past 30 years, numerous studies have focused on the toxicities of polycyclic aromatic hydrocarbons (PAH). Laboratory and field studies have helped elucidate the detrimental effects of these chemicals on growth, reproduction and immune response. Polycyclic aromatic hydrocarbons are in the priority list of chemicals to be studied by...
Resource Type:: Dissertation
Full Text:: of Immunotoxicity for Polycyclic Aromatic Hydrocarbons in Rainbow Trout (Oncorhynchus inykiss

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

Creator:: Norby, Tyler S.
Abstract:: Polycyclic aromatic hydrocarbons (PAHs) are significant pollutants in aquatic environments. Many are carcinogenic and lead to DNA fragmentation and adduct formation in marine and freshwater organisms. Previous research demonstrates that rainbow trout (Oncorhynchus mykiss) compensate to long-term PAH dietary exposures and reduce the DNA damage. The aim of this study...
Resource Type:: Masters Thesis
Full Text:: Aromatic Hydrocarbon Mixture Abstract approved: Lawrence R. Curtis Polycyclic aromatic hydrocarbons

From pesticide degradation products to legacy toxicants and emerging contaminants : novel analytical methods, approaches, and modeling

Creator:: Forsberg, Norman D.
Abstract:: Environmental toxicologists and public health officials are responsible for assisting in the identification, management, and mitigation of public health hazards. As a result, there is a continued need for robust analytical tools that can aid in the rapid quantification and characterization of chemical exposure. In the first research phase, we...
Resource Type:: Dissertation
Full Text:: approach for modeling oxygenated polycyclic aromatic hydrocarbon formation in bioavailable chemical

Semi-volatile organic compounds and developing organisms : accumulation in California mountain tadpoles in the field and fish embryo exposures in the laboratory

Creator:: Stanley, Kerri A.
Abstract:: The atmospheric transport and deposition of semi-volatile organic compounds (SOCs), including current and historic use pesticides, polychlorinated biphenyls (PCBs) and polycyclic aromatic hydrocarbons (PAHs), to mountain ecosystems may result in the exposure of tadpoles to these SOCs. This exposure has been implicated in amphibian population declines in California. Tadpoles encounter...
Resource Type:: Dissertation
Full Text:: dry weight basis…………………………………………………………….63 3.6 Polycyclic aromatic hydrocarbon (PAH) ratios and

Comparison between lichen, conifer needles, resin-based passive air sampling devices (PASDs), and snow to monitor semi-volatile organic compounds (SOCs) in the atmosphere

Creator:: Schrlau, Jill E.
Abstract:: The purpose of this research was to compare four different media that were used to monitor SOC atmospheric concentrations in remote ecosystems. The accumulation of semi-volatile organic compounds, including pesticides, polycyclic aromatic hydrocarbons (PAHs) and polychlorinated biphenyls (PCBs), was investigated in lichen, 2-year old conifer needles, resin-based passive air sampling...
Resource Type:: Masters Thesis
Full Text:: Polycyclic Aromatic Hydrocarbon Vapors. Environ. Sci. Technol. 1999, 33, (1), 195-197. (31) Daly, G. L

Analysis of semi-volatile organic contaminants and their accumulation in remote aquatic ecosystems of the western US

Creator:: Ackerman, Luke K.
Abstract:: Many pesticides, polychlorinated biphenyls (PCBs), polybrominated diphenyl ethers (PBDEs), and polycyclic aromatic hydrocarbons are persistent, bio-accumulative, and toxic. These semi-volatile organic compounds (SOCs) can undergo atmospheric transport and deposition in cold, remote ecosystems. A better understanding of their accumulation in the fish of these ecosystems is important to better predict...
Resource Type:: Dissertation
Full Text:: , L. L.; Collier, T. K. Establishing the causal relationship between polycyclic aromatic hydrocarbon

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Creator:: Madeen, Erin
Abstract:: The objective of this work is to add to the body of translational data between high dose animal model research and the environmentally relevant human metabolism of the persistent pollutant dibenzo[def,p]chrysene (DBC). We furthered the knowledge of gene/exposure interactions by determining the carcinogenesis risk based on Cyp1b1 genotype following in...
Resource Type:: Dissertation
Full Text:: High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and

Creating Isogenic Cell Cultures for Functional Studies of DNA Mismatch-Repair

Creator:: Sarver, Kimberly
Abstract:: Colorectal cancer (CRC), the third leading cause of cancer death in the USA, depends on early detection for patient survival. Early detection is improved with the identification of high risk individuals. Risk of CRC development is a complex interaction between an individual’s genetics and environmental exposures. Polycyclic Aromatic Hydrocarbons (PAHs)...
Resource Type:: Undergraduate Thesis and Presentation

Zero Kinetic Energy Photoelectron Spectroscopy of Polycyclic Aromatic Hydrocarbons

Creator:: Harthcock, Colin
Abstract:: In this dissertation, I describe spectroscopic studies of jet-cooled polycyclic aromatic hydrocarbons (PAH) and one nitrogen substituted PAH (PANH) using pulsed field zero kinetic energy (ZEKE) photoelectron spectroscopy and resonantly enhanced multiphoton ionization (REMPI) spectroscopy. Recently, there has been a demand for far-infrared (FIR) spectral information of astrophysically relevant molecules...
Resource Type:: Dissertation
Full Text:: Spectra for Polycyclic Aromatic Hydrocarbon Neutrals, Cations, and Anions. J. Phys. Chem. 1996, 100, 2819

Human in vivo Pharmacokinetics of [¹⁴C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Micro-Dosing

Creator:: Madeen, Erin, Corley, Richard A., Crowell, Susan, Turteltaub, Kenneth, Ognibene, Ted, Malfatti, Mike, McQuistan, Tammie J., Garrard, Mary, Sudakin, Dan, and Williams, David E.
Abstract:: Dibenzo(def,p)chrysene (DBC), (also known as dibenzo[a,l]pyrene), is a high molecular weight polycyclic aromatic hydrocarbon (PAH) found in the environment, including food, produced by the incomplete combustion of hydrocarbons. DBC, classified by IARC as a 2A probable human carcinogen, has a relative potency factor (RPF) in animal cancer models 30-fold higher...
Resource Type:: Article

ScholarsArchive@OSU

Assessing mechanisms of immunotoxicity for polycyclic aromatic hydrocarbons in rainbow trout (Oncorhynchus mykiss)

Antioxidant enzyme response in rainbow trout (Oncorhynchus mykiss) after subchronic exposure to an environmentally-relevant polycyclic aromatic hydrocarbon mixture

From pesticide degradation products to legacy toxicants and emerging contaminants : novel analytical methods, approaches, and modeling

Semi-volatile organic compounds and developing organisms : accumulation in California mountain tadpoles in the field and fish embryo exposures in the laboratory

Comparison between lichen, conifer needles, resin-based passive air sampling devices (PASDs), and snow to monitor semi-volatile organic compounds (SOCs) in the atmosphere

Analysis of semi-volatile organic contaminants and their accumulation in remote aquatic ecosystems of the western US

Translational Studies of the High Molecular Weight Polycyclic Aromatic Hydrocarbon, Dibenzo[ def,p] Chrysene; Carcinogenesis and Metabolism

Creating Isogenic Cell Cultures for Functional Studies of DNA Mismatch-Repair

Zero Kinetic Energy Photoelectron Spectroscopy of Polycyclic Aromatic Hydrocarbons

Human in vivo Pharmacokinetics of [¹⁴C]Dibenzo[def,p]chrysene by Accelerator Mass Spectrometry Following Oral Micro-Dosing

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