Index Catalog // ScholarsArchive@OSU

The spatial resolution of information in a diffusive cytoplasm

Creator:: Sellers, Drew L.
Abstract:: Every cell is faced continuously with the task of transducing a vast number of external signals into appropriate intracellular responses. In mammalian cells, membrane bound receptors modulate the production of secondary messenger molecules, such as cyclic AMP (cAMP). Cell signaling through second messengers relies on the diffusion of such second...
Resource Type:: Dissertation
Full Text:: function together in feedback ioop to direct the motor-protein dependent transport of melanosomes

The microtubule system and the canalicular mdr2 P-glycoprotein play a role in the intracellular transport and biliary secretion of α-Tocopherol and phosphatidylcholine in rats and mice

Creator:: Mustacich, Debbie J.
Resource Type:: Dissertation
Full Text:: , aTocopherol transport protein; VLDL, very low density lipoprotein. 14 The preferential incorporation of a

Silicon and germanium uptake and cell growth by the marine diatom Nitzschia frustulum

Creator:: Jeffryes, Clayton S.
Abstract:: Diatoms are single celled algae that form cell walls made primarily of silicon dioxide (SO₂). The metabolic machinery that gives diatoms the ability to biogenically form highly ordered solid silica from soluble silicon extracted from their external environment provides a unique platform to create novel nanostructured materials inexpensively and with...
Resource Type:: Masters Thesis
Full Text:: (OH)4, and a silaffin protein within the Silicon Deposition Vesicle

Temperature-salinity effects on net protein synthesis and viability of Vibrio marinus mp-1, an obligately psychrophilic marine bacterium

Creator:: Cooper, Mary Faith
Abstract:: The relationship of temperature and salinity to protein synthesis was determined for cells of Vibrio marinus, MP-1. Protein synthesis was measured by the incorporation of radioactive proline into hot trichloroacetic acid precipitable material. At all salinities protein synthesis occurred at 15°C and 20°C but not at 25°C. The critical temperature...
Resource Type:: Masters Thesis
Full Text:: in protein synthesis at 24°C may result from inhibition of cellular transport mechanisms. A

Cholinesterase activity and sodium transport in the frog skin

Creator:: Wyse, Beatrice Milas
Abstract:: By salt depleting the animals or by injecting them with aldosterone, I was able to increase the active transport of sodium across the isolated skin. The potential difference was increased by 37% and 43% respectively and the net sodium flux by 69% and 62%. Exposure of frogs to 50 mM...
Resource Type:: Masters Thesis
Full Text:: ACTIVITY AND SODIUM TRANSPORT IN THE FROG SKIN Abstract approved (Major Professor) By salt depleting the

Effect of pharmaceuticals and natural products on multidrug resistance mediatedtransport in Caco-2 and MDCKII-MDR1 drug transport models

Creator:: Fan, Ying
Abstract:: This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
Resource Type:: Dissertation
Full Text:: P-gp substrates by interacting with MDR1 protein. EGCG and xanthohumol can modulate the transport

Control of p53 tumor suppressor and peroxiredoxin activity through shifts incellular redox balance

Creator:: Stoner, Christopher S.
Abstract:: Aerobic organisms have evolved many sensory mechanisms that allow response to oxidants in the environment. One area of interest is the relationship between the activity of the tumor suppressor protein p53 and the redox state of thioredoxin. Human p53 activity is severely compromised in budding yeast lacking thioredoxin reductase. Evidence...
Resource Type:: Dissertation
Full Text:: suppressor protein p53 and the redox state of thioredoxin. Human p53 activity is severely compromised in

The effects of carbonated beverages on arterial oxygen saturation, serum hemoglobin concentration and maximal oxygen consumption

Creator:: Waibler, Max
Abstract:: Elite milers, Sir Roger Bannister and Joseph Falcon, have stated that the consumption of carbonated beverages hinders the performance of aerobic events. Oxygen transport is purportedly impaired by the consumption of carbonated beverages. The research on carbonated beverages has been limited to the effects on the digestive system, gastric emptying,...
Resource Type:: Masters Thesis
Full Text:: hinders the performance of aerobic events. Oxygen transport is purportedly impaired by the consumption of

Regulation of skeletal muscle protein degradation by u-calpain and development of a skeletal muscle-specific inducible expression system

Creator:: Xiao, Ying-Yi
Abstract:: The first goal of this study was to understand the role of u-calpain in skeletal muscle protein degradation in cultured muscle cells. Several strategies were developed to down-regulate endogenous u-calpain activity and m-calpain activity in rat myotubes. These included over-expression of antisense u-calpain (AnsL), dominant negative u-calpain (DN-u-CL), antisense 30K...
Resource Type:: Dissertation
Full Text:: protein (9). According to the physiological condition of animals, this replacement portion could be even

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

Creator:: Farid, Samar Farghali
Abstract:: This thesis describes in vitro and in vivo evaluation of a gastric retention formulation (GRF) developed at Oregon State University. The formulation was prepared from xanthan gum and locust bean gum as gelling agents and other formulation ingredients were added, then it was originally vacuum oven dried. The effect of...
Resource Type:: Dissertation

ScholarsArchive@OSU

The spatial resolution of information in a diffusive cytoplasm

The microtubule system and the canalicular mdr2 P-glycoprotein play a role in the intracellular transport and biliary secretion of α-Tocopherol and phosphatidylcholine in rats and mice

Silicon and germanium uptake and cell growth by the marine diatom Nitzschia frustulum

Temperature-salinity effects on net protein synthesis and viability of Vibrio marinus mp-1, an obligately psychrophilic marine bacterium

Cholinesterase activity and sodium transport in the frog skin

Effect of pharmaceuticals and natural products on multidrug resistance mediatedtransport in Caco-2 and MDCKII-MDR1 drug transport models

Control of p53 tumor suppressor and peroxiredoxin activity through shifts incellular redox balance

The effects of carbonated beverages on arterial oxygen saturation, serum hemoglobin concentration and maximal oxygen consumption

Regulation of skeletal muscle protein degradation by u-calpain and development of a skeletal muscle-specific inducible expression system

Development and in vivo testing of novel hydrochlorothiazide gastric retention formulations in healthy volunteers and stage I hypertensive patients

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