Dendrimers are well-defined, polymeric nanomaterials currently being investigated for biomedical applications such as medical imaging, gene therapy, and tissue targeted therapy. Initially, higher generation (size) dendrimers were of interest because of their drug carrying capacity. However, increased generation was associated with increased toxicity. The majority of studies exploring dendrimer toxicity...
Inherent nanomaterial characteristics, composition,
surface chemistry, and primary particle size,
are known to impact particle stability, uptake, and
toxicity. Nanocomposites challenge our ability to predict
nanoparticle reactivity in biological systems if they
are composed of materials with contrasting relative
toxicities. We hypothesized that toxicity would be
dominated by the nanoparticle...
Inherent nanomaterial characteristics, composition,
surface chemistry, and primary particle size,
are known to impact particle stability, uptake, and
toxicity. Nanocomposites challenge our ability to predict
nanoparticle reactivity in biological systems if they
are composed of materials with contrasting relative
toxicities. We hypothesized that toxicity would be
dominated by the nanoparticle...
Full Text:
toxicity of engineered silver
nanoparticles
Josephine A. Bonventre • JosephB. Pryor •
Bryan J. Harper
Inherent nanomaterial characteristics, composition, surface chemistry, and primary particle size, are known to impact particle stability, uptake, and toxicity. Nanocomposites challenge our ability to predict nanoparticle reactivity in biological systems if they are composed of materials with contrasting relative toxicities. We hypothesized that toxicity would be dominated by the nanoparticle...
Dendrimers are well-defined, polymeric nanomaterials currently being investigated for their biomedical applications. Initially, higher generation (size) dendrimers were of interest because of their drug carrying capacity. However, increased generation was associated with increased toxicity. The objective of the present study was to investigate the role of surface charge and generation...
A Cr₂0₃, and cellulose fibre mixture was used with cattle, in
three grazing and two semi-restricted experiments, to study the mode
of its excretion, the possibility of using it in a once-daily dosing and
grab-sample regime to estimate fecal output and in a field experiment
to test a hypothesis involving...
Distracted driving is an adverse driving behavior that is widely known to impair the safety of all roadway users and traffic flow. Despite the extensive research efforts on the prevalence and effects of distracted driving on roadway safety and performance, the number of vehicular crashes and fatalities resulting from distracted...
Residents in South Falls City, a small town in the foothills of Oregon's Coast Range, battle intense flooding during the rainy season. Disagreements about surface water management pit neighbor against neighbor, but preliminary evidence suggests that groundwater flooding is an underlying cause. OSU researchers pair the emerging literature on groundwater...
High severity fire is a historical and integral disturbance process in coniferous
forest types. Compounded disturbances such as multiple fires or post-disturbance
management activities are increasingly common, but ecological responses are not well
understood and may represent novel types of disturbances. I studied bird and small
mammal communities in the...
Premise of research. We sought to determine the role of flowering in recovery of understory herbs from a major disturbance and to determine the effects of plant and environmental factors on flowering patterns.
Methodology. We counted flowering and nonflowering shoots in permanent plots eight to 10 times over a 30-year period for...