In a comparison of the mammalian and fish immune systems many similarities and differences are found. While most of the differences occur in the acquired or lymphoid arm of immunity, the nonlymphoid immune systems of fish and mammals share many similarities. For instance, both animal groups use phagocytic neutrophils and...
The immune systems of various teleost fish have been studied in some detail for
the past several decades. One aspect of fish immunity, that of endogenously produced
modulating factors, has recently received a great deal of attention. Understanding the
functions and roles of endogenous factors that regulate fish immunity is...
DNA fragments of the gene for VP2, the major capsid protein of Infectious
Pancreatic Necrosis Virus (IPNV), were expressed in Escherichia coli and
characterized immunologically with antisera made to different serotypes of
IPNV. The entire VP2 gene was excised from the plasmid pUC19/A+SΔK and
fragmented with restriction enzyme Sau3A1. The...
The characteristics of an inhibitor of infectious pancreatic necrosis virus (IPNV)
found in normal rainbow trout serum (RTS) were studied. The serum inhibitor had a
molecular weight of approximately 150 kDa and was dependent on divalent cations,
either Ca²⁺ or Mg²⁺. It was stable at temperatures up to 50°C and...
Immunological memory has been shown to occur
unequivocally in mammals. However, controversy exists regarding
the capability of fish to elicite a memory response. This study
demonstrates that memory does occur
rainbow trout, Oncorhynchus rnykiss.
Trout injected with a T-dependent antigen,
trinitrophenylated keyhole-limpet hemocyanin, (TNP-KLH) (100
μg/fish) were able to produce...
Currently little is known about the mechanisms and locations of
lymphocyte development in teleosts. In this study several aspects of the
underlying factors which govern B lymphocyte development in trout
were investigated which included: the isolation and characterization of
immunoglobulin heavy chain (IgH) genes, the recombination activating
genes 1 and...
This thesis tests the hypothesis that innate immunity may be enhanced
immediately following a stressful event. The experiments characterize the acute
effects of the fight or flight response on some immunological and endocrine
parameters in rainbow trout (Oncorhynchus mykiss). Plasma cortisol and
catecholamines were elevated within seconds of the initiation...
Indole-3-carbinol (I3C) inhibits chemically induced tumor
formation in rodents and rainbow trout. This study examines the
effect of I3C and its analog, indole-3-acetonitrile (I3N) on
xenobiotic-metabolizing enzyme systems. The modulation of these enzyme
systems have been shown to have significant effects on the
interaction of chemical carcinogens and cellular constituents....
The effects of a sublethal concentration of dieldrin (0. 2 ppb)
in the water on the growth and body composition of underyearling rainbow
and cutthroat trout held in aquaria and fed different rations of tubificid
worms or Oregon moist pellets were studied at Oak Creek Fisheries
Research Laboratory, Oregon State...