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  • Unraveling tissue regeneration using chemical genetics

    Creator:
    Mathew, Lijoy K.
    Abstract:
    The emerging field of regenerative medicine is mainly approached by two different aspects. First is the use of stem cell based models to generate a suite of differentiated cells for therapeutic applications and the alternative approach is to utilize the non-mammalian models that have the inherent capacity to regenerate their...
    Resource Type:
    Dissertation
    Full Text:
    : Unraveling Tissue Regeneration Using Chemical Genetics. Abstract approved: Robert L

  • Chemical and biological approaches to identify vertebrate tissue regeneration pathways

    Creator:
    Sengupta, Sumitra
    Abstract:
    Numerous human conditions would be improved if therapies to encourage tissue regeneration were available. The goal of regenerative medicine is to encourage the body's intrinsic ability to repair and restore tissues lost by disease, injury or aging. While certain vertebrates have the inherent capacity to regenerate, mammals do not. To...
    Resource Type:
    Dissertation
    Full Text:
    provide us a better understanding of the biology of regeneration. Since the fundamental processes and

  • Consequences of miRNA misregulation on embryonic development and aging

    Creator:
    Franzosa, Jill A.
    Abstract:
    microRNAs (miRNAs), ~21-24 nucleotide-long RNAs that post-transcriptionally regulate gene expression, have rapidly become one of the most extensively studied mechanisms of the past decade. Since their discovery as temporal regulators of post-embryonic development in C. elegans, miRNAs have been functionally implicated in almost every cellular process investigated to date. miRNAs...
    Resource Type:
    Dissertation
    Full Text:
    deficits in regeneration capacity, we performed mRNA and small RNA sequencing on regenerating and non

  • Regeneration biology of Erigeron decumbens var. decumbens, an endangered plant of the Willamette Valley

    Creator:
    Clark, Deborah Louise, 1950-, Finley, Karen K., and Ingersoll, Cheryl A.
    Abstract:
    Erigeron decumbens var. decumbens, the Willamette daisy, is known only from the Willamette Valley of Oregon. Herbarium records, from the 1800's until 1934, indicate that the Willamette daisy was once common and widely distributed throughout the Willamette Valley (Clark et al. 1993). However, between 1934 and 1980, this taxon was...
    Resource Type:
    Technical Report
    Full Text:
    REGENERATION BIOLOGY OF ERIGERON DECUMBENS VAR. DECUMBENS