Flavin-containing monooxygenase (FMO, EC1.14.13.8) comprises a family of
xenobiotic-metabolizing enzymes that catalyze the oxygenation of a wide variety of
xenobiotics, most commonly nitrogen and sulfur. Mammals express five different FMOs
in a species- and tissue- specific manner. FMO2, is expressed predominantly in lung and
differs from other FMOs in that...
Background: Alcohol is a nonessential nutrient widely consumed throughout the world. Chronic alcohol abuse is associated with numerous adverse skeletal effects. However, prior to this study, the effects of alcohol abuse on intracortical bone remodeling in an animal model had not been investigated. Reduced intracortical bone remodeling could impair repair...