The Baculoviridae comprise a diverse group of occluded DNA viruses that contain large double-stranded DNA genomes of 80 - 180 kb and may encode up to 180 gene products. To understand how baculoviruses replicate and process their genomes and the gene products that are involved in these events, a series...
Baculoviruses comprise a diverse group of pathogens
infectious for members of the insect orders Lepidoptera, Hymenoptera
and Diptera. Of the three subgroups, two (subgroup A, nuclear
polyhedrosis virus (NPV) and subgroup B, granulosis virus (GV) are
occluded in a crystalline protein structure while the remaining
subgroup (subgroup C, non-occluded virus)...
The Baculoviridae is a family of DNA viruses which are obligate
pathogens for a variety of insects. Baculovirus strains came to the
attention of researchers because they provided a nonchemical
alternative for the biological control of insect pests of agriculture
and forestry (Ignoffo, 1968); however, recently they have been studied...
The yeast two-hybrid system was used to examine
interactions between the nine proteins involved in baculovirus DNA
replication. From the six proteins required for DNA replication,
four protein-protein interactions were identified, including an
interaction between LEF-1 and LEF-2, LEF-3 and itself, LEF-3 and
P143 (Helicase), and an interaction between IE-1...
Regulation of expression of three genes in the polyhedron
envelope protein (PEP) gene region of the Orgyia pseudotsugata
multinucleocapsid nuclear polyhedrosis virus (OpMNPV) was
examined. These genes include open reading frame (ORF) 1 (encoding
p21), ORF 2 (encoding gp16), and ORF 3 (encoding the polyhedron
envelope protein). The effect of...
This book is based on a project to completely annotate what is known about the function of the ~150 genes encoded by the genome of the most commonly investigated baculovirus, AcMNPV. Once the annotation was completed (summarized in Chapter 12), the material was organized into a series of chapters integrating...