Technology is a key determinant of comparative advantage among nations. As information technology improves and the nations of the world become economically integrated, concern arises over the dissipation of high-income economies’ technological advantage. The three essays in this dissertation explore the trade and technology relationship, which is essential to economic...
Oregon strawberries are known for their high quality, intense flavor, sweetness, and rich red color. With optimal weather conditions, including rainy and mild seasons, Oregon has one of the best strawberry farming environments. Amongst the factors for a suitable strawberry farming environment, soil significantly influences strawberry growth and quality. The...
Cells of the ventrolateral dermomyotome delaminate and migrate into the limb buds where they give rise to all muscles of the limbs. The migratory cells proliferate and form myoblasts, which withdraw from the cell cycle to become terminally differentiated myocytes. The myogenic lineage colonizes pre-patterned regions to form muscle anlagen...
Pyrenophora tritici-repentis is a necrotrophic fungus causal to the disease tan spot of wheat, whose contribution to crop loss has increased significantly during the last few decades. Pathogenicity by this fungus is attributed to the production of host-selective toxins ( HST), which are recognized by their host in a genotype-specific...
Embryonic development, where organs and major structures begin to develop, requires precise coordination of numerous gene regulatory pathways. Fendrr is an long non-coding RNA (lncRNA) that plays a role in regulating gene expression in mesodermal tissues during early embryonic development in mouse. The lateral plate mesoderm (LPM) is an earlier...
Degeneration of the intervertebral disc (IVD) is a phenomenon that has yet to be adequately addressed. Treatment options remain limited and incomplete. The ability to effectively cryopreserve IVDs would allow for better allograft transplantations and storage of samples for research purposes. This study aimed to assess how cryopreservation with different...
As the link between human microbiomes and health has become more established, the interest in applying statistical approaches to microbiome data to understand the mechanisms behind these links has grown. However, microbiome data is often of unmanageable size, and consequently, producing quality lower dimensional representations of samples is a significant...
Marine diseases are becoming more frequent, and tools for identifying pathogens and disease
reservoirs are needed to help prevent and mitigate epizootics. Meta-transcriptomics
provides insights into disease etiology by cataloguing and comparing sequences from suspected
pathogens. This method is a powerful approach to simultaneously evaluate both the
viral and bacterial...
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, understanding zoonoses, and opportunities
for vaccine development. Curr Opin Virol. 2012 Jun; 2(3):344–52. doi
Mutation of repetitive DNA by repeat-induced point mutation (RIP) is a process that occurs in many filamentous fungi of the Ascomycota during the sexual cycle. Concurrently, direct DNA repeats are often deleted by homologous recombination at high frequency during the sexual cycle. Thus, the processes of RIP and deletion compete...
The aim of this work is to review current knowledge relating the established cancer hallmark, sustained cell proliferation
to the existence of chemicals present as low dose mixtures in the environment. Normal cell proliferation is under tight
control, i.e. cells respond to a signal to proliferate, and although most cells...
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that are characterized
by a basic leucine-zipper region. It comprises members of the
Jun protein