Molecular chirality plays a critical role in chemistry, biology, and medicine. To study and better understand conformational chirality, it is necessary to obtain structurally interesting molecules that exhibit this form of chirality. Our lab utilizes total synthesis and methodological development to obtain conformationally chiral natural products of interest. We believe...
The major components of wheat flour are keys to its functionality in processing and product quality. The major components, other than the lipids, are polymers: starch, protein, and non-starchy polysaccharides (NSP). In wheat NSP are primarily arabinoxylans (AX). These components are compartmentalized in the grain but are forced into close...
Cementitious materials are often characterized through the use of advanced analytical techniques to understand the macro-, micro-, and nano-scale properties, including phase formation during hydration, and subsequent potential deterioration mechanisms which can affect service life. A major limitation with using such analytical techniques to quantify solid phases in cementitious systems...
Dearomatization reactions exist broadly in biosynthesis and chemical synthesis. The highly functionalized atoms of arenes can be masked by it aromaticity, and upon dearomatization, those reactive atoms can be readily applied to bond formation and further manipulation. The total synthesis of (–)-cephalotaxine and (–)- homoharringtonine is described via an oxidative...
The emergence of high explosives on the battlefield can be defined both literally and figuratively as a seismic event in the landscape of modern warfare. High explosives first came into common use in war in 1914. By the end of World War I just four years later, more than 2.5...
Biological, serological, and molecular characteristics
of the P4 pathotype of pea seedborne mosaic potyvirus
(PSbMV) were investigated. The characterization allowed P4
to be differentiated from other pathotypes of the same
virus.
P4 was distinguished from P1 on the basis of host
symptomatology. It induced varied, but often distinctive
symptoms in...
This dissertation describes the racemic and enantioselective synthesis cavicularin. Cavicularin is a macrocyclic bisbibenzyls family member natural product. It has been an attractive synthetic target due to its intriguing structure: the macrocyclic core imparts sufficient strain on the system to force one benzene rings to adopt a boat-shaped conformation, out...
This thesis consists of two major components. The first part is concerned with video object instance segmentation (VOS), which is the task of assigning per-pixel labels perframe of a video sequence to indicate foreground object instance membership, given the first frame ground truth mask. VOS has myriad applications, from video...
The Klamath Experiment Station (KES) staff are pleased to present the annual report on KES research programs conducted in 1991. This is the fifth in a current series of special reports dating back to 1987. We hope our readers will glean useful information from the findings of research efforts in...