Passage of blood through a sorbent device for removal of bacteria and endotoxin by specific binding with immobilized, membrane-active, bactericidal peptides holds promise for treating severe blood infections. Peptide insertion in the target membrane and stable binding is desirable, while membrane disruption and release of degradation products to the circulating...
For the past six years a bacterial infection has been the cause
of large losses of adult, spawning, American shad (Alosa
sapidissima) in the Coos, Millicoma and Smith Rivers of Oregon.
There was a sizable commercial fishery for shad in these rivers
and losses of fish due to this infection...
Sepsis is a blood infection caused by circulating pathogens and cell wall fragments that affects over 1 million patients per year in the United States. When bacterial cell membranes are lysed by antibiotics, cell wall fragments containing lipopolysaccharides (LPS) are released. As a result, the capture of LPS is critical...