We developed, synthesized, and tested a multifunctional nanostructured lipid nanocarrier- based system (NLCS) for efficient delivery of an anticancer drug and siRNA directly into the lungs by inhalation. The system contains: (1) nanostructured lipid carriers (NLC); (2) anticancer drug (doxorubicin or paclitaxel); (3) siRNA targeted to MRP1 mRNA as a...
Succinic acid, a low molecular weight dicarboxylic acid was used to leach out
heavy metals from Willamette Valley soil (contaminated separately with lead, copper,
and zinc) in form of water-soluble organo-metal complexes. The research tasks included
developing synthetic contaminated soils representative of those found at Superfund sites
and making heavy...