Published March 1955. Facts and recommendations in this publication may no longer be valid. Please look for up-to-date information in the OSU Extension Catalog: http://extension.oregonstate.edu/catalog
This report presents a characterization of the quantum mechanical
analog of the Gibbs canonical density. The approach is
based on a method developed by D.S. Carter for the case of classical
statistical mechanics, which considers composite mechanical systems
composed of mechanically and statistically independent components.
After a brief introductory chapter,...
Carter Lake, a freshwater, coastal dune-margin lake,
was sampled at the beginning and end of the summer of 1986
to determine the sediment characteristics and benthic
macroinvertebrate abundance, biomass, variety, and
diversity. The distributions of major benthic habitats were
estimated by snorkeling in June and July, 1986. Water
temperature and...
Declines or extinctions of the native intertidal estuary blue mud shrimp, Upogebia pugettensis, have been observed or are suspected in all of its populations over the species’ range. These declines are associated with the introduced Asian bopyrid isopod parasite, Orthione griffenis, which effectively castrates females. Baseline estimates of population abundances...
Lycopodium alkaloids have shown widespread and noteworthy biological activity, consisting of over 250 known natural products. Moreover, their structural complexity and diversity have attracted considerable attention from numerous laboratories including our own. Recently, we have developed a unified approach that would provides access to numerous, previously unprepared C₁₀-functionalized lycopodium alkaloids....
This dissertation is separated into two parts according to the two major distinct research projects. In Part I, the full account of synthetic studies toward C10-functionalized lycopodium alkaloids is described. In Part II, the detailed discussion on the exploration of the Pummerer cyclization methodology and its application to the total...
Mandelalide A has attracted considerable interest from the synthetic community due to its intriguing structure and important cytotoxic activity. Madeirolide A, a structurally related macrolide, shows promising antifungal activity but no appreciable anticancer activity. This dissertation describes synthetic studies toward mandelalide A, madeirolide A and their hybrid structures.
Part I...
More than 30 members of the diverse amphidinolide family of biologically active macrolides have been isolated over last three decades. From this family, amphidinolides C and F stand among the most complex and densely functionalized affiliates. Recently, we have accomplished the first total synthesis of amphidinolide F. The all-carbon framework...
Effective methods for the enantiopure formation of substituted piperidine rings are significantly important due to their presence in alkaloid products. A valuable method to form these ring systems would be via an intramolecular heteroatom Michael addition from the corresponding enone or enal. Described herein is a methodolgy that has been...
Part I of this dissertation includes the chronological synthetic background of mandelalide A as well as the synthesis of the C1-C14 glycosylated southern subunit of mandelalide. A key aspect of the synthesis includes a novel silver-catalyzed cyclization (AgCC) of a propargylic benzoate to construct the substituted cis-pyran ring system present...