Over the course of the last century, a successful history of fire suppression has contributed to unsuccessful present day control over wildfire. In the absence of fire and the janitorial and ecological services it provides, drier inland forests are shifting in species composition and exceeding densities that cannot survive and...
Giant chinquapin (Chrysolepis chrysophylla) is an evergreen hardwood often found as a shrubby understory component of coniferous forests in the Pacific Northwest United States. Due to its ability to sprout quickly after disturbances such as fire and logging it is often viewed as a pest by forest managers. Like its...
Fuel accumulation and climate shifts are predicted to increase the frequency of high-severity fires in ponderosa pine (Pinus ponderosa Dougl. ex Laws) forests of central Oregon. The combustion of fuels containing large downed wood can result in intense soil heating, alteration of soil properties, and mortality of microbes. Previous studies...
Background information is presented that provides historical perspectives on the field of mycology in the Pacific Northwest and its role in forest management. The series of events and decisions that have led to previous studies (or lack of studies) in the field also dictate the directions of current research. Culture,...
Ectomycorrhizal fungi (EmF) form symbioses with trees. These symbioses profoundly influence forest ecology. Certain EmF form specialized profusions of hyphae, known as ectomycorrhizal fungal mats (mats) which are visible to the naked eye, alter forest soil biogeochemistry, substantially contribute to soil microbial biomass/respiration and support unique microbial communities. Piloderma and...
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David D. Myrold JaneE. Smith
Ectomycorrhizal fungi (EmF) form symbioses with
Fire suppression in the last several decades has resulted in unprecedented accumulations of organic matter on the landscape, leading to an increase in large, intense wildfires. This study investigated the soil microbial community (using phospholipid fatty acid analysis) across recently burned forests on the eastern slope of the Cascade Range...
Land managers, scientists, and the interested public are confronted with uncertainty about the impacts of salvage logging on soil productivity. In recent years, stand-replacing wildfires in the western United States have increased in frequency, prompting the need to evaluate the effect of post-fire treatments on forest ecosystem recovery. This study...
Chemical compounds produced by organisms, or natural products, are excellent sources of inspiration for anticancer pharmaceutical discovery (Rodrigues et al., 2016). Microtubule targeting agents are a specific class of compounds, often discovered from natural sources, that have been developed as clinically successful anticancer therapies (Steinmetz and Prota, 2018). In the...
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JaneE. Ishmael, Ph.D.
Chemical compounds produced by organisms, or natural products, are
Cancer is the second leading cause of death in the United States. To date, over 60% of current anticancer drugs were inspired by the discovery of chemical structure from nature, commonly known as a natural product. This work represents the biological characterization of several marine natural product compounds and their...
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JaneE. Ishmael
Cancer is the second leading cause of death in the United States. To date
Natural products from both terrestrial and marine sources represent a significant source of novel drug leads, and have previously been developed into clinically-approved agents for the treatment of various human diseases. This work represents the biological characterization of the mechanistic basis for activity of several natural product structures in models...