In this report, three studies are presented that aid in the development of drug discovery and their synthesis. In each, the importance of the marriage between computations and experiments is highlighted. Continued efforts in this vein are essential for future efforts towards improving human health.
The first case study investigated...
Species declines and extinctions have been recorded across taxa as evidence of an ongoing global biodiversity crisis. Amphibians are at the forefront of these declines with nearly one third of amphibian species estimated to be at risk of extinction. While many factors contribute to population declines and extinctions, the role...
Recent conflicts in America concerning the environment (the harvesting of old growth timber in the Pacific Northwest, or the proposed opening of public lands in southern Utah to mining interests, for instance) have precipitated a personal examination of "historical others" (Jensen 64), individuals that possess very different sensibilities from a...
Brownian motion is the movement of a particle in a fluid resulting from collisions with surrounding molecules. It has modern applications in simulating fluid dynamics and the motion of proteins in biophysics. Brownian motion simulations generally evolve the initial state by applying Newton’s second law to every particle. These simulations...
A 2014 Pew Research poll revealed large gaps between public opinion and scientific opinion over environmental and biomedical issues (Funk and Rainie). Similarly, a number of recent popular books have described a growing public mistrust in scientific expertise (Mooney; Storr; Specter). Why is it, then, that so much of the...
Analysis of the pinniped remains from site 35 LNC 14 reveal
the presence of four species: Eumetopias jubata (Stellar sea lion),
Zalophus californianus (California sea lion), Callorhinus ursinus
(Northern fur seal),'and Phoca vitulina (Harbor seal). Ratios
based on minimum number of individuals calculations disclose a
high incidence of mature Stellar...
This study examined debris flows occurring in a 125 km² study area in the Blue River watershed in the western Cascade Mountains of Oregon over a 50-year period. Debris flow occurrence was found to be concentrated in a distinct zone of high activity occupying approximately half of the study area,...
A cultural landscape analysis of two historic cemeteries in St. Paul, Oregon demonstrates that the residents of this early community were unknowingly using grave markers to express their worldview and the identities that they felt were most important. Because of the historical and cultural development of this community as the...
St. Joseph's College was located within St. Paul, Oregon, the first Roman Catholic mission in the Pacific Northwest. The St. Paul mission was finally established in 1839 by Father Francois Blanchet, four years after the French-Canadian settlers in the area, appropriately known as French Prairie, had requested the presence of...