Advanced computer architectures are centered around the parallel computer systems. This project is focused on the experiment on two parallel computer architectures : Sequent Balance 21000 shared memory multiprocessor and Cogent XTM distributed system.
A set of benchmark programs are implemented using "C" language and Dynix parallel programming library on...
Triple-negative breast cancer (TNBC) is a particularly aggressive molecular subtype of malignant cells that tends to proliferate quickly and is commonly resistant to traditional chemotherapy leading to relapses in prognosis more frequently than other forms of breast cancer (BCa) [1][2][3]. Current treatment options include surgical resection of cancerous tissue and...
We developed an integration-based line detection algorithm. Existing line detection methods such as the Hough Transformation (HT) and its variants are insensitive to image noise. The reason is that HT finds lines by calculating the gradient of the image and assumes that the region where the gradient is the steepest...
Cell signaling under external stimulation is a critical mechanism that governs many biological processes such as cell proliferation, cell migration, and cell apoptosis, etc. For multicellular organisms, the ability to synchronize heterogeneous individual cellular responses through intercellular communication is crucial to maintain normal functionality. However, even though the biological pathways...
Cell migration is fundamental for physiological processes such as immune re-sponses, wound healing and development. It is also a critical characteristic of metastatic cancer cells. An extensive amount of studies have focused on 2D sub-strates in order to understand the mechanism of cancer metastasis. However, much less is known about...
At the intersection of basic science research and clinical relevance, cancer metastasis and cell invasion is a multifaceted problem that has been investigated for the past several decades. Importantly, cancer cell plasticity, the ability of a single cell to change its phenotype without genetic mutations in response to environmental cues,...
Childhood obesity prevalence is significantly higher among adolescent 12-19 years old than younger age groups. Youth athletes are overlooked by childhood obesity prevention programs. WAVE~Ripples for Change (WAVE) program is a 2-y obesity prevention intervention with high school (HS) soccer players (14-19y) using a mixed virtual- and physical-world learning environment...
This dissertation presents a phase domain in-loop-bandwidth spread-spectrum clock generation technique. In this proposed technique, a charge-based discrete-time loop filter is proposed to enable the phase domain in-loop-bandwidth spread-spectrum modulation without a delta-sigma modulator or time-to-digital converter. The in-loop-bandwidth modulation technique maximizes the loop bandwidth to improve phase noise suppression...
Enantioenriched sp³-hybridized carbenoid reagents CR1R2MX (X = nucleofuge, M = electrofuge) of different types were investigated for the synthesis of polysubstituted alkyl chains by iterative stereospecific reagent-controlled homologation (StReCH) and for the stereospecific connective synthesis of alkenes by eliminative cross-coupling.
In the first part, putative enantioenriched α-chloroalkyllithiums (CHRLiCl) were employed...
Biorhythm theory proponents believe that humans have
a 23-day physical cycle, a 28-day emotional cycle, and a
33-day intellectual cycle. According to biorhythm theories
a person in the positive portion of any single cycle, the performance potential is enhanced for those tasks related to
that particular rhythm. When each cycle...