Index Catalog // ScholarsArchive@OSU

Investigations of the AhR-induced Treg : transcriptional regulation and suppressive mechanisms

Creator:: Rohlman, Diana
Abstract:: The aryl hydrocarbon receptor (AhR) has recently been described as a novel therapeutic target, given the potent suppression of multiple immune-mediated diseases following activation by the prototypic ligand, 2,3,7,8-tetrachlorodibenzo-p-dioxin (TCDD). In the parent-into-F1 graft-versus-host (GVH) model, suppression of the cytotoxic T-lymphocyte (CTL) response is associated with the presence of CD25⁺CTLA-4⁺IL-10⁺Foxp3[superscript...
Resource Type:: Dissertation
Full Text:: , may directly influence gene expression during CD4 + T-cell activation and differentiation, thereby

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Creator:: Maxwell, Joseph R.
Abstract:: T cells are one of the key cells in the immune system. Although they are not the first line of defense against a pathogen, their functions can greatly enhance the phagocytosis and destruction of pathogens as well as the development of antibody responses. Furthermore, even when responding T cells have...
Resource Type:: Dissertation
Full Text:: Costimulation and Adjuvants in the Development of T Cell Effector and Memory Responses. Abstract approved

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

Creator:: Prell, Rodney A.
Resource Type:: Dissertation
Full Text:: antigen presenting cell (APCs). Complete T cell activation results in proliferation, differentiation and

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

Creator:: Shepherd, David M.
Abstract:: The immune system has been identified as a very sensitive target for the toxic effects of 2,3,7,S-tetrachlorodibenzo-p-dioxin (TCDD). Exposure to TCDD has been shown to disrupt the generation of both cell-mediated and humoral T cell-dependent immunity in laboratory animals; however, the mechanism remains unknown. In this dissertation, the hypothesis is...
Resource Type:: Dissertation
Full Text:: , the hypothesis is tested that TCDD exposure alters T cell activation and differentiation either

Positive and negative regulators of adipocyte differentiation in primary culture

Creator:: Suryawan, Agus
Resource Type:: Dissertation
Full Text:: differentiation have been investigated using established cell lines or preadipocytes in primary culture. It is

Differentiation of porcine stromal vascular cells in primary culture

Creator:: Suryawan, Agus
Abstract:: The objective of this study was to examine optimum conditions for primary culture of porcine preadipocytes. Dorsal subcutaneous adipose tissue was obtained from biopsies of 40-50 kg pigs and digested with collagenase in Krebs Ringer Bicarbonate buffer. Isolated stromal vascular cells were cultured in different test media. Stromal vascular cells...
Resource Type:: Masters Thesis
Full Text:: was found to be crucial in order to achieve a high rate of cell differentiation. A plating time of 24

Regulation of adipose stromal-vascular cell differentiation in culture

Creator:: Akanbi, Kamil Agbolade
Abstract:: Primary cultures of stromal-vascular (S-V) cells from adipose tissue were used to investigate the regulation of preadipocyte development. Differentiation of S-V cells was found to be under hormonal control. Insulin and glucocorticoids are essential for S-V cell differentiation in culture. S-V cells from both newborn and mature pig adipose tissue...
Resource Type:: Dissertation
Full Text:: , 1992. Title: Regulation of Adipose Stromal-Vascular Cell Differentiation in Culture Abstract

Regulation of 3T3-L1 preadipocyte differentiation in culture

Creator:: Chen, Chu-liang, 1961-
Resource Type:: Dissertation
Full Text:: retinoic acid receptor (RAR) a. The time- dependent inhibition of cell differentiation by TCDD was

Site-directed mutagenesis of chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) in different functional domain

Creator:: Wang, Zhaohong
Resource Type:: Masters Thesis
Full Text:: cell number, and it is regulated by fat cell replication and differentiation. Adipocyte

The influence of aryl hydrocarbon receptor activation on T cell fate

Creator:: Funatake, Castle J.
Abstract:: 2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) and related compounds are well-recognized for their immunosuppressive activity, which is mediated through an intracellular receptor and transcription factor, aryl hydrocarbon receptor (AhR). Laboratory animals exposed to TCDD are less resistant to infection and have severely impaired humoral and cell-mediated immune responses. This dissertation addressed the hypothesis that...
Resource Type:: Dissertation
Full Text:: Hydrocarbon Receptor Activation on T Cell Fate. approved: 2,3,7, 8-Tetrachlorodibenzo-p-dioxin (TCDD) and

ScholarsArchive@OSU

Investigations of the AhR-induced Treg : transcriptional regulation and suppressive mechanisms

The role of costimulation and adjuvants in the development of T cell effector and memory responses

Investigation of the mechanism of 2,3,7,8-tetrachlorodibenzo-p-dioxin-induced immunotoxicity in C57B1/6 mice : effects on T cell activation

The effects of 2,3,7,8-tetrachlorodibenzo-p-dioxin on T cell activation

Positive and negative regulators of adipocyte differentiation in primary culture

Differentiation of porcine stromal vascular cells in primary culture

Regulation of adipose stromal-vascular cell differentiation in culture

Regulation of 3T3-L1 preadipocyte differentiation in culture

Site-directed mutagenesis of chicken ovalbumin upstream promoter transcription factor I (COUP-TFI) in different functional domain

The influence of aryl hydrocarbon receptor activation on T cell fate

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