Search Constraints

Start Over
Filtering by: Committee Member Taylor, Babara J Remove constraint Committee Member: Taylor, Babara J

Search Results

  • Formation and modification of enduracididine, a nonproteinogenic amino acid

    Creator:
    Tan, Ying
    Abstract:
    Molecular genetic and enzymological techniques have been employed to study antibiotic biosynthesis. In this thesis, we studied the formation and modification of the nonproteinogenic amino acid enduracididine (End), which exists in two important antibiotics, mannopeptimycins (MPPs) and enduracidin. Sequence analysis of the MPP gene cluster revealed that the product of...
    Resource Type:
    Masters Thesis
    Full Text:
    .; Washington DC, 2003 6. McDevitt, D.; Payne, D. J.; Holmes, D. J.; Rosenberg, M. Novel targets for the

  • Genomics-enabled exploration of insect toxicity in the Pseudomonas fluorescens group

    Creator:
    Rangel, Lorena I.
    Abstract:
    Pseudomonas is a diverse genus of Gamma proteobacteria that are ubiquitous in the natural environment, including soil, water, plant surfaces, and animals. The Pseudomonas fluorescens group is a diverse collection of seven subgroups and more than 50 named species. This group is known for their production of a variety of...
    Resource Type:
    Masters Thesis
    Full Text:
    function of the Manatee program (J. Craig Venter Institute, Gaithersburg, Maryland). Tc genes present in

  • Unraveling the endogenous functions of the aryl hydrocarbon receptor (AHR) and characterizing a novel long non-coding RNA (slincR) that contributes to AHR-mediated toxic responses in zebrafish

    Creator:
    Garcia, Gloria R.
    Abstract:
    The aryl hydrocarbon receptor (AHR) is a ligand activated transcription factor that is a member of the basic helix-loop-helix PER-ARNT-SIM (bHLH/PAS) protein family of cellular sensors. The AHR is conserved across multiple animal phyla and is required for proper vertebrate development. A structurally diverse group of chemicals, including polycyclic aromatic...
    Resource Type:
    Dissertation

  • Functional and Structural Analyses of Three Distinct proteins by Biochemical and Biophysical Techniques

    Creator:
    Codding, Sara Jone
    Abstract:
    The focus of this dissertation was to understand protein function and structure ona molecular level. To do this successfully, a variety of biochemical and biophysicaltechniques were employed. A wide variety of techniques were applied to study theproteins of interest in this dissertation to probe protein-protein interactions, proteinfunction, protein structure, and...
    Resource Type:
    Dissertation
    Full Text:
    Padmanarayana for our friendly conversations, and Naomi J. Marty, for always reminding me that life is short

  • Protein Disorder in the Evolution of Dynein Regulation

    Creator:
    Jie, Jing
    Abstract:
    Intrinsically disordered proteins (IDP) are a class of proteins that lack a three-dimensional structure and their prevalence and diverse functions in the cell have only been discovered relatively recently. The intermediate chain (IC) subunit of the microtubule motor protein complex dynein contains an N-terminal disordered region, N-IC, which is central...
    Resource Type:
    Dissertation
    Full Text:
    : _____________________________________________________ Elisar J. Barbar Intrinsically disordered proteins (IDP) are a class of proteins that lack

  • Influence of weed density on efficacy of two soil-applied herbicides

    Creator:
    Burrill, L. C.
    Abstract:
    Several studies were conducted to determine the effect of weed density on herbicide efficacy. Diuron [3-(3, 4- dichlorophenyl) -1, 1- dimethylurea] was tested on various densities of Italian ryegrass (Lolium multiflorum Lam. ) under greenhouse and field conditions. Cycloate (S-ethyl N-ethylthiocyclohexanecarbamate) was tested on green foxtail (Setaria viridis (L. )...
    Resource Type:
    Masters Thesis
    Full Text:
    preparation of the manuscript. I am grateful to Dr. Ronald J. Burr, Dr. William W. Chilcote and Dr. Lyall

  • Identification of the plasminogen activator inhibitor produced by the day 14 bovine embryo

    Creator:
    Mendoza, Ruben
    Abstract:
    Day 12-14 bovine embryos produce urokinase-type plasminogen activator (uPA) and an uPA-plasminogen activator inhibitor (PAI) complex. The type of PAI, -1 or -2, in the complex has not been determined therefore the objective of this research was to identify the PAI produced by the Day 14 bovine embryo. In experiment...
    Resource Type:
    Masters Thesis

  • Community profiles of ammonia oxidizers across high-elevation forest-to-meadow transects

    Creator:
    Mintie, Ann
    Abstract:
    In recent years considerable interest has been shown in the diversity of ammonia-oxidizing bacteria in soil communities. The majority of the research has been carried out in Northern Europe where soils have received high atmospheric inputs of nitrogen over the past two centuries. In contrast, although much work has been...
    Resource Type:
    Masters Thesis
    Full Text:
    Oxidizers Across High-Elevation Forest-to- Peter J. Bottomley In recent years considerable interest has

  • Assembly and Regulation of WW-PPXY Complexes in Hippo Signaling

    Creator:
    Baker, Kasie J.
    Abstract:
    The Hippo signaling pathway is an evolutionarily conserved regulator of cell growth, proliferation, and apoptosis. A key function of the pathway is to regulate the subcellular distribution and activity of Yorkie in Drosophila or Yes-associated protein (YAP) and transcription co-activator with PDZ-binding motif (TAZ) in mammals. The dysregulation of the...
    Resource Type:
    Dissertation
    Full Text:
    THE DISSERTATION OF Kasie J. Baker for the degree of Doctor of Philosophy in Biochemistry and

  • Toxicogenomic Biomarkers Associated with PAH Carcinogenic Potential in a 3D in Vitro Bronchial Epithelial Model

    Creator:
    Chang, Yvonne
    Abstract:
    The environmental health science community recognizes polycyclic aromatic hydrocarbons (PAHs) as a re-emerging class of environmental pollutants due to their persistence and prominence in mixtures of concern. Due to their widespread distribution in the environment, exposure to PAHs often occur as complex chemical mixtures. Exposures are linked to numerous adverse...
    Resource Type:
    Dissertation
    Full Text:
    . Staci Simonich, Dr. David Williams, Dr. Barbara Taylor, and Dr. Molly Megraw for their contributions