A combination of genetical and biochemical methods were
utilized in investigating house fly resistance to naphthalene. The
inheritance of resistance was determined by crossing a naphthalene
resistant strain of Musca domestica L. with a susceptible mutant
marker strain. Biochemical comparisons were made on substrains
isolated from the progeny of these...
Previous investigations have shown that exposure to DDT results
in increased activity in soluble and microsomal enzyme in insects.
These responses in DDT-resistant Triatoma infestans
nymphs and in adults of DDT-resistant Musca domestica (the common
house fly) are accompanied by increased RNA and protein synthesis.
The phenomenon has been termed...
Rat liver microsomes are shown to contain an enzyme system
which converts the cyclodiene insecticides, aldrin, heptachlor and
isodrin to their corresponding epoxides, dieldrin, heptachlor epoxide,
and endrin. The microsomal fraction of 450 milligrams of liver from
male rats epoxidates 80 percent of a 20 to 50 microgram aldrin substrate...
In vitro studies of Mobam (4-benzo(b)thienyl N-methylcarbamate) metabolism have demonstrated that at least three ether soluble metabolites are formed in a microsomal system fortified with reduced triphosphopyridine nucleotide (NADPH). One of the metabolites was identical to 4HBT (4-hydroxy benzothiophene), the phenol of Mobam. The other two metabolites did not possess...
In vitro studies of Mobam (4-benzo(b)thienyl N-methylcarbamate)
metabolism have demonstrated that at least three ether soluble
metabolites are formed in a microsomal system fortified with reduced
triphosphopyridine nucleotide (NADPH). One of the metabolites was
identical to 4HBT (4-hydroxy benzothiophene), the phenol of Mobam.
The other two metabolites did not possess...
Assay conditions and analytical methods established for the
study of epoxidation of the insecticides aldrin and heptachlor, by
rat liver microsomes have been employed to study the same reaction
catalyzed by trout liver microsomes. At 37° C and pH 8.0, rainbow
trout liver microsomes, incubated with 54.8 millimicromoles of
either...
The polyunsaturated fatty acids (PUFA) are known to be required
for larval growth and normal wing development in several
species of Lepidoptera but most of the basic information necessary
for a complete understanding of this nutritional phenomenon has not
been gathered. This includes the role of each of the essential...