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Filtering by: Funding statement This work was supported by funding from NIH grant HLBI U01HL100001. S.H.O. is an Investigator of the HHMI. M.C.C. was supported by NIH grant F30 DK103359-01A1. Remove constraint Funding statement: This work was supported by funding from NIH grant HLBI U01HL100001. S.H.O. is an Investigator of the HHMI. M.C.C. was supported by NIH grant F30 DK103359-01A1.

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  • HendrixDavidEECSPRC2RequiredMaintain.pdf

    Creator:
    Das, Partha Pratim, Hendrix, David A., Apostolou, Effie, Kuintzle, Rachael, and et al.
    Abstract:
    Polycomb Repressive Complex 2 (PRC2) function and DNA methylation (DNAme) are typically correlated with gene repression. Here, we show that PRC2 is required to maintain expression of maternal microRNAs (miRNAs) and long non-coding RNAs (lncRNAs) from the Gtl2-Rian-Mirg locus, which is essential for full pluripotency of iPSCs. In the absence...
    Full Text:
    ://dx.doi.org/10.1016/j.celrep.2015.07.053 This is an open access article under the CC BY license (http