Three experiments were conducted to study the influence of dietary fatty acids on the production performance and immune response of chickens. In experiment I, forty day-old broiler chicks were fed diets containing 5% of either animal fat + conjugated linoleic acid (CLA) (Diet I), sunflower oil (Diet II), flax oil...
Inflammation is the body's response to injury and is characterized by pain, swelling, redness, and heat. Eicosanoids are lipid mediators of inflammation. Leukotrienes (LT) are 20-carbon eicosanoids produced from arachidonic acid (AA), an n-6 fatty acid (FA), and eicosapentaenoic acid (EPA), an n-3 FA. LT produced from AA are proinflammatory...
Arachidonic acid (ARA) and docosahexaenoic acid (DHA) are polyunsaturated fatty acids required for proper embryonic development, specifically neurodevelopment. However, little is known regarding their conversion to other metabolites during embryogenesis. The oxidation of ARA gives rise to the biologically active eicosanoids and the oxidation of DHA gives rise to the...
In this five-week feeding study male New Zealand rabbits were
fed diets containing cyclopropene fatty acids (CPFA), diets containing
cholesterol, and diets with both CPFA and cholesterol added to test
the effect of CPFA on cholesterol metabolism and atherosclerosis
induction. When CPFA-fed animals were compared with control
animals, they tended...
In the presence of internal or external stressors, the body requires sources of energy that aide cells to combat inflammation. Fatty acids are an important source of energy and are vital components of cell membranes. Dietary fatty acids (n-6 and n-3) are of importance in immune function because they are...
Three studies were designed to evaluate the promoting
effect of cyclopropenoid fatty acids (CPFA) on avian myeloblastosis
virus (AMV) infection in White Leghorn chickens.
In the first study effects on growth parameters, blood serum
and erythrocyte lipid composition of White Leghorn chickens
were investigated at 100 ppm and 300 ppm...
The DNA repair capabilities of rainbow trout (Salmo gairdneri)
were studied vising the method of autoradiography. Trout were fed a
semi-purified control diet containing 0 ppm, 50 ppm, or 300 ppm
cyclopropenoid fatty acids (CPFA) for 6-9 weeks. Liver slices were
prepared and exposed in vitro to a control treatment,...
Nonalcoholic fatty liver disease (NAFLD) is characterized by the accumulation of excess neutral lipids within the parenchymal cells of the liver. The primary etiology is diet-induced and most often exists as a comorbidity with obesity, metabolic syndrome, and/or Type 2 Diabetes. The development of excess liver lipid can be self-limiting...