Anecdotal accounts of tiludronate administration via intravenous regional limb
perfusion (IVRLP) exist despite a lack of information regarding safety for synovial
structures in the perfused area. The objective of this study was to determine whether
tiludronate concentrations in synovial structures after IVRLP with low dose (0.5 mg,
LDT) or high...
Full Text:
VeterinaryMedicine, Oregon State University,
Corvallis, OR, USA
∗ Current affiliation: Matamata Veterinary
Anecdotal accounts of tiludronate administration via intravenous regional limb
perfusion (IVRLP) exist despite a lack of information regarding safety for synovial
structures in the perfused area. The objective of this study was to determine whether
tiludronate concentrations in synovial structures after IVRLP with low dose (0.5 mg,
LDT) or high...
Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous
synoviocytes from the affected stifle is an attractive cell source for tissue engineering
replacement fibrocartilage. However, the diseased state of these cells may impede
in vitro fibrocartilage formation. Synoviocytes from 12 osteoarthritic (“oaTSB”) and
6 normal...
Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous
synoviocytes from the affected stifle is an attractive cell source for tissue engineering
replacement fibrocartilage. However, the diseased state of these cells may impede
in vitro fibrocartilage formation. Synoviocytes from 12 osteoarthritic (“oaTSB”) and
6 normal...
Full Text:
Jennifer J. Warnock1, Gerd Bobe2 and Katja F. Duesterdieck-Zellmer1
1 College of VeterinaryMedicine
Anecdotal accounts of tiludronate administration via intravenous regional limb
perfusion (IVRLP) exist despite a lack of information regarding safety for synovial
structures in the perfused area. The objective of this study was to determine whether
tiludronate concentrations in synovial structures after IVRLP with low dose (0.5 mg,
LDT) or high...
To determine effects of intraarticularly administered tiludronate on articular cartilage in vivo, eight healthy horses were injected once with tiludronate (low dose tiludronate [LDT] 0.017 mg, n = 4; high dose tiludronate [HDT] 50 mg, n = 4) into one middle carpal joint and with saline into the contralateral joint....
Meniscal tears are a common cause of stifle lameness in dogs. Use of autologous
synoviocytes from the affected stifle is an attractive cell source for tissue engineering
replacement fibrocartilage. However, the diseased state of these cells may impede
in vitro fibrocartilage formation. Synoviocytes from 12 osteoarthritic (“oaTSB”) and
6 normal...