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  • Search for a repressor regulator of invasion in Mycobacterium avium

    Creator:
    Tripathi, Sanjai T.
    Abstract:
    Mycobacterium avium is an intracellular pathogen that is associated with disseminated infection, especially in patients with acquired immunodeficiency syndrome (AIDS). It appears that patients with AIDS acquire M. avium mostly through the intestinal tract, and that bacteria enter the intestinal wall at the terminal ileum. Previous studies have found that...
    Resource Type:
    Masters Thesis

  • Alternative splicing in the obligate biotrophic oomycete pathogen, Pseudoperonospora cubensis

    Creator:
    Cumbie, Jason S.
    Abstract:
    Oomycetes are some of the most devastating pathogens, causing upwards of billions of dollars of damage each year to plants. They also diminish ecological diversity and health through the destruction of trees and shrubs. The genome sequence of Pseudoperonospora cubensis, an obligate plant pathogen and causative agent of downy mildew...
    Resource Type:
    Dissertation
    Full Text:
    first step for discovering candidate virulence genes. Through these efforts, the novel discovery was

  • A molecular study of viral proteins in the pathogenesis of infectious hematopoietic necrosis virus

    Creator:
    Chiou, Pinwen Peter
    Abstract:
    The role of viral proteins in the pathogenesis of infectious hematopoietic necrosis virus (IHNV) was studied at the molecular level. The expression of the viral genes at the protein and RNA level, and their cellular localization, were characterized to further our understanding of viral pathogenesis. The pathogenic effect of individual...
    Resource Type:
    Dissertation
    Full Text:
    degree of Doctor of Philosophy in Microbiology presented on December 11. 1996. Title: A Molecular Study

  • Surface-exposed proteins in the pathogenesis of Mycobacterium avium subsp. hominissuis

    Creator:
    McNamara, Michael J.
    Abstract:
    Mycobacterium avium subsp. hominissuis (MAH) is a pervasive environmental bacterium that can cause opportunistic infections in humans. Among the most robust and hardy members of the Mycobacterium genus, M. avium can persist and thrive in a range of challenging environments, including many which place it in direct contact with humans....
    Resource Type:
    Dissertation
    Full Text:
    responsible for the export of several classes of proteins, many of which play an integral role in virulence

  • Mycobacterium avium genes upregulated upon infection of Acanthamoeba castellanii demonstrate a common response to the intracellular environment

    Creator:
    Tennant, Rachel C.
    Abstract:
    Mycobacterium avium is a ubiquitous environmental organism found in both water and soil. It can cause disease in patients with previous pulmonary conditions, as well as immunosupressed patients, with the most prevalent being AIDS patients. Studies have indicated that passage through amoeba, a common environmental protozoa, increases virulence of M....
    Resource Type:
    Masters Thesis
    Full Text:
    Master of Science in Microbiology presented on March 4, 2005. Title: Mycobacterium avium genes

  • Mechanisms for the interaction of environmental mycobacteria with host cells

    Creator:
    Harriff, Melanie J.
    Abstract:
    Environmental mycobacteria are important opportunistic pathogens for many hosts, including humans, cattle, and fish. Two well-studied species are Mycobacterium avium subsp. avium, a significant cause of disseminated bacterial disease in patients with AIDS, and Mycobacterium avium subsp. paratuberculosis, the cause of Johne’s disease in cattle. Many other species that are...
    Resource Type:
    Dissertation
    Full Text:
    custom DNA microarray containing probes for known mycobacterial virulence determinants was developed

  • Characterization of the response mediated by the plant disease susceptibility gene LOV1

    Creator:
    Gilbert, Brian M.
    Abstract:
    Victoria blight, caused by fungus Cochliobolus victoriae, is a disease originally described on oats and recapitulated on Arabidopsis. Victoria blight is used as a model plant disease that conforms to an inverse gene-for-gene interaction. C. victoriae virulence is dependent upon its production of victorin, a host-specific toxin that induces programmed...
    Resource Type:
    Dissertation
    Full Text:
    . victoriae virulence is dependent upon its production of victorin, a host-specific toxin that induces

  • The ecology of parasite interactions within Chinook salmon

    Creator:
    Hurst, Charlene N.
    Abstract:
    The within-host interactions that can occur as a result of mixed infections in wildlife likely influence the outcome of an infection. We investigated the infection frequency and outcome as well as the potential mechanisms regulating mixed infections with two Ceratonova shasta genotypes within the Chinook salmon host. Previous research in...
    Resource Type:
    Dissertation
    Full Text:
    Hurst for the degree of Doctor of Philosophy in Microbiology presented on August 7, 2014. Title