The catabolism of glucose by proliferating and resting cells of
two strains of Saccharomyces cerevisiae has been examined, with
respect to the nature and participation of concurrent glucose pathways
by means of the radiorespirometric method. The nicotinamide
nucleotide content, and nicotinamide nucleotide oxidase activities
in these cells were also examined....
The variety of natural disasters provide different sets of characteristics and properties with unique challenges. One significant difference between hazard types is prewarning lead time, the amount of time individuals have from a potential warning to the disaster occurring. Rapid onset disasters may not provide an official warning about a...
Transportation systems are facing safety and operational challenges with a cost of billions of dollars annually in lost production time and wasted fuel. Infrastructure expansion, previously held as a panacea to most transportation challenges has lost its appeal due to financial, land-use and environmental constraints. Interest is surging in intelligent...
Mitotic recombination is a common autosomal mutation in mammalian cells involving crossover events between homologous chromosomes. This process can convert a cell with a heterozygous deficiency to one with a homozygous deficiency, and thus often represents the second step in tumor suppressor gene inactivation. In this study I examined the...
Surface tension kinetics exhibited by selected stability mutants of T4 lysozyme at the air-water interface were monitored with DuNoüy tensiometry. Mutant lysozymes were produced by substitution of isoleucine at position 3 with cysteine, leucine, tryptophan and glycine. Each substitution resulted in an altered structural stability quantified by a change in...
Kernel hardness (KHA) is a major factor determining break flour yield (BFY) and end-use quality of common wheat (Triticum aestivum L.). Within the soft wheat class, genotypes with consistently softer grains than common soft wheat are considered to be 'extra-soft'. In addition, 'extra-soft' wheats have greater BFY than common soft...
The details of the 1700 Cascadia Subdction Zone earthquake and tsunami can be better constrained using data from tsunami sand sheets, provided knowledge of the waveform, estuary geometry and bed roughness controls on the deposition pattern of the sand sheet. In this study, we use the hydrodynamic and sediment transport...
Streams and rivers play a critical role in global carbon (C) cycling by processing, storing, and transporting C. Headwater streams which make up more than 95% of the length of streams and rivers worldwide have disproportionate influence on fluvial C dynamics. The hyporheic zone (HZ) of headwater streams is a...
Highway construction projects require temporary changes in roadway characteristics, such as the number of operational lanes, lane path, lane width, shoulder width, and posted speed limit. These modifications which are often temporary in nature have the potential to impact driving performance. Many research efforts have focused on developing standards to...
Lynch individuals have a predisposition to developing colorectal and other cancers due to inherited defects in their mismatch repair (MMR) system. Although mutations in MMR have been directly implicated in Lynch Syndrome, the precise mechanism(s) of MMR functions have yet to be elucidated. One essential complex, MutL (a dimer of...