This dissertation examined the association between HAP and respiratory health, both using simple proxy metrics, such as cooking fuel types, and actual measurements, such as household and personal measures of PM2.5 and BC. We found that simple proxy metrics can predict a portion of HAP levels, and associations with respiratory...
It is considered best practice when designing pedestrian access at intersections to provide two curb ramps at each street corner. In Oregon, there are many locations where long ramp runs cause curb ramps to be set back a significant distance from the apex of the intersection corner to meet this...
Transportation systems are facing safety and operational challenges with a cost of billions of dollars annually in lost production time and wasted fuel. Infrastructure expansion, previously held as a panacea to most transportation challenges has lost its appeal due to financial, land-use and environmental constraints. Interest is surging in intelligent...
Multiple-input multiple-output (MIMO) communication systems have recently been considered as one of the most significant technology breakthroughs for modern wireless communications, due to the higher spectral efficiency and improved link reliability. The sphere decoding algorithm (SDA) has been widely used for maximum likelihood (ML) detection in MIMO systems. It is...
The first goal of this study was to understand the role of u-calpain in skeletal muscle protein degradation in cultured muscle cells. Several strategies were developed to down-regulate endogenous u-calpain activity and m-calpain activity in rat myotubes. These included over-expression of antisense u-calpain (AnsL), dominant negative u-calpain (DN-u-CL), antisense 30K...
This thesis details my investigation of some pharmaceuticals and natural products on the transport of drugs which are substrates of P-glycoprotein (P-gp), such as cyclosporin A (CSA) and digoxin by using Caco-2 and MDCKII-MDR1 drug transport models. Three objectives were performed to address this goal. The first objective was to...
Public concern has recently focused upon the presence
of radioactive radon in homes. The Environmental
Protection Agency and others have researched this health
hazard. Radon gas is given off during typical household
water uses such as showering, bathing, dishwashing, and
clothes washing. However, few studies have been performed
on radon...
A novel switched-R-MOSFET-C input branch is proposed for low-voltage and high-linearity applications. The tunability is achieved by varying the clock duty cycle using an automatic tuning circuit. This tuning method does not involve a change in gate voltage, and is therefore particularly suitable for low-voltage applications. The advantages of the...
Reliability of sub-micron analog circuits is directly related to impact ionization and
the subsequent changes in threshold voltage and drain current of n-MOSFET devices.
This thesis presents theory of the hot-electron effects on the device characteristics and
circuit performance, explores several approaches to improve performance at both the
device and...