The numerous different types of nanomaterials and paucity of reliable in vivo information on toxicity has resulted in enduring uncertainties associated with health and safety risks, thereby slowing progress in nanotherapeutic assessment and development. This dissertation explores how the embryonic zebrafish model can be applied to prioritize commonly used nanomaterial...
Glioblastoma Multiform
• Type of aggressive brain cancer
• Five year survival rate of 4.70%
• Not often detected until it’s in the later stages when
the symptoms appear
• Surgery is not an effective option due to invasion and
proliferation of glioblastoma cells outside of the tumor
mass before...
The fish early-life stage (FELS) test (Organisation for Economic Co-operation and Development [OECD] test guideline 210) is the
primary test used internationally to estimate chronic fish toxicity in support of ecological risk assessments and chemical management programs.
As part of an ongoing effort to develop efficient and cost-effective alternatives to...
The fish early-life stage (FELS) test (Organisation for Economic Co-operation and Development [OECD] test guideline 210) is the
primary test used internationally to estimate chronic fish toxicity in support of ecological risk assessments and chemical management programs.
As part of an ongoing effort to develop efficient and cost-effective alternatives to...
Full Text:
ANNOTATING ADVERSE OUTCOME PATHWAYS FOR EARLY
FISH DEVELOPMENT
DANIEL VILLENEUVE,y DAVID C. VOLZ,z MICHELLE
The fish early-life stage (FELS) test (Organisation for Economic Co-operation and Development [OECD] test guideline 210) is the primary test used internationally to estimate chronic fish toxicity in support of ecological risk assessments and chemical management programs. As part of an ongoing effort to develop efficient and cost-effective alternatives to...
Gravid adult female Euphausia pacifica were collected off Newport, Oregon, USA and transferred to the laboratory, where females spawned eggs, eggs hatched, and larvae were reared at 10.5 degrees C. We fed 4 cohorts of larvae to excess with a combination of phytoplankton species and monitored them daily until they...
This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American Chemical Society and can be found at: https://doi.org/10.1021/acs.est.5b00499
Full Text:
of PAH Contaminated Soil Results in Increased
Genotoxicity and Developmental Toxicity
Leah
This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American Chemical Society and can be found at: https://doi.org/10.1021/acs.est.5b00499
Full Text:
Contaminated Soil Results in Increased
Genotoxicity and Developmental Toxicity
Chibwe, L., Geier, M. C
This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American Chemical Society and can be found at: https://doi.org/10.1021/acs.est.5b00499
IMPORTANCE:
Muscle pain, fatigue, and weakness are common adverse effects of statin medications and may decrease physical activity in older men.
OBJECTIVE:
Determine whether statin use is associated with physical activity, longitudinally and cross-sectionally.
DESIGN, SETTING, AND PARTICIPANTS:
Men participating in the Osteoporotic Fractures in Men Study, a multicenter prospective...