Long-term stimuli of many systems leads to decreased cellular responsiveness, or desensitization. We characterized the desensitization of angiotensin II (Ang 11)-mediated inositol phospholipid (IP) hydrolysis in cultured human aortic smooth muscle cells (HASMC). Although it has been suggested that the desensitization induced by long-term Mg II exposure may result partially...
This thesis reports a portion of a general ecological study of
a stream under conditions of controlled flow and low levels of organic
enrichment. It is concerned with the effects of experimental variations
of light intensity and concentration of soluble organic enrichment
imposed on seasonal variations of temperature and total...
An attempt has been made to elucidate the biosynthetic precursor
of ethylene in the mold P. digitatum. By application of basic
radiotracer methodology and the utilization of several specifically
labeled radiochemical substrates, it has been possible to demonstrate
that the internal carbon atoms of C-4 dicarboxylic acids such
as succinate,...
One hundred and fifty-one weanling rats of both sexes were fed
control diets or diets containing 160 ppm diethylnitrosamine (DEN) or
150 ppm N-2-fluorenyl-acetamide (FAA). The carcinogen level was
calculated so that the LD₅₀ should be achieved at about 17 weeks.
Each carcinogen treatment was incorporated with three different diet...
Existing methods for the estimation of relative participation of
glucose catabolic pathways make use of yield data of respiratory
¹⁴CO₂ or intermediary ¹⁴C products derived from glucose substrates
specifically labeled with ¹⁴C. Cumulative yields of respiratory
¹⁴CO₂ observed at the end of time course of complete substrate
utilization are analyzed...