Dibenzo[def,p]chrysene (DBC) is a highly potent, but less prevalent, environmental carcinogen belonging to a class of compounds known as Polycyclic Aromatic Hydrocarbons (PAHs). They are highly ubiquitous and arise as a byproduct of natural and anthropogenic combustion processes. Previous studies have documented carcinogenic effects upon in utero exposure of PAHs....
Epidermal RNA samples from FVB/N mice treated with PAH standards and
environmental PAH mixtures were harvested and purified using Trizol extraction and
RNeasy mini prep kit purification. Epidermal RNA integrity was low (RIN mean 3.5),
indicating significant RNA degradation and the need to modify handling, collection, and
processing of skin...
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)
AhR (56.0˚C)
Acknowledgements
• Lisbeth Siddens
• Professor William Baird
Baird Lab
• Dr
Epidermal RNA samples from FVB/N mice treated with PAH standards and
environmental PAH mixtures were harvested and purified using Trizol extraction and
RNeasy mini prep kit purification. Epidermal RNA integrity was low (RIN mean 3.5),
indicating significant RNA degradation and the need to modify handling, collection, and
processing of skin...
Full Text:
with environmental PAH mixtures
Andrew Larkina,b, Lisbeth K. Siddensb, Sharon K. Kruegerc, DavidE
Epidermal RNA samples from FVB/N mice treated with PAH standards and
environmental PAH mixtures were harvested and purified using Trizol extraction and
RNeasy mini prep kit purification. Epidermal RNA integrity was low (RIN mean 3.5),
indicating significant RNA degradation and the need to modify handling, collection, and
processing of skin...
Aquatic and riparian systems in the western United States have been highly modified by anthropogenic impacts since Euro-American settlement. Ecological restoration is a practice that has been widely conducted around the world to mitigate the degradation of these systems. The majority of stream restoration efforts have focused on improving in-stream...
The concept of reducing laboratory operations into microfluidic devices has been an attractive area of research for several decades. Due to several advantages of porous-media microfluidic devices including low mass, portability, power-free fluid transport, and the ability to store dried reagents in the porous structures, these devices show great promise...
Objective: Alcohol and cannabis use and co-use among college students is prevalent in the United States (Bravo et al., 2021). These substances have been linked to poor collegiate academic performance in past research. The present study examines varying levels of single-substance alcohol use and alcohol and cannabis co-use in their...
The progress report that follows includes research results ranging from unproved ideas to scientific papers published during the tenure of this contract, The end of the contract year finds several facets of our work in various states of preparation, therefore the reader is cautioned that all except the published papers...
It is current practice to transport juvenile anadromous salmonids in transplantation and to help them bypass dams. Essentially nothing is known about the effects that transportation could have on the ability of the fish to outmigrate and be fit for survival in the marine environment. Procedures involved in transporation subject...
The progress report that follows includes research results ranging from unproved ideas to scientific papers published during the tenure of this contract. The end of the contract year finds several facets of our work in various states of preparation, therefore the reader is cautioned that all except the published papers...