In this work, I address foundational concerns at the interface of institutions, governance structure, transaction costs, and efficiency in public-private contracting. Following transaction cost economic perspective, I build and justify the theoretical models explaining that institutions may affect the economic performance of public-private contracting through the effect of transaction costs....
Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
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, Catherine E. Peishoff, Susan Pieniazek, Randy J. Read, Chenghua Shao, Steven
Sheriff, Oliver Smart, Stephen
Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
Full Text:
Nakamura,28 Anthony Nicholls,15
Marc Nicklaus,29 Robert T. Nolte,30 Anil K. Padyana,31 Catherine E
Crystallographic studies of ligands bound to biological macromolecules (proteins and nucleic acids) represent an important source of information concerning drug-target interactions, providing atomic level insights into the physical chemistry of complex formation between macromolecules and ligands. Of the more than 115,000 entries extant in the Protein Data Bank (PDB) archive,...
A majority of eighteenth-century novels remain in regular print over two hundred years since their inception. Yet with the possible exception of Robinson Crusoe, they have largely fallen out of popularity, rarely appearing on "The Summer's Hottest Reading" lists or receiving celebrity endorsement. I consider Ian Watt's foundational study, The...
Utilizing Danio rerio (zebrafish) as a model organism has gained popularity recently, however a lack of research into their immune response pathways had led to the discovery of subclinical infections, and has potentially confounded results. We conducted a study to determine the cytokine expression from TLR activation in order to...
Large-scale safety-net programs such as Temporary Assistance for Needy Families (TANF) and the Supplemental Nutrition Assistance Program (SNAP) have been shown to alleviate the negative effects of low-wage jobs and unemployment on poor American households. However, less is known about the role of “emergency” safety net programs, such as rental...
Climate change affects the choice of land-use not only through its direct effect on the productive potential of land, but also through human actions that alter the landscape. In this dissertation, I estimate current climate's effect on the economic net returns to alternative land-use systems in the United States. Then...
Causal inference is an important analytical tool to bridge the gap between prediction and decision-making. However, learning a causal network solely from data is a challenging task. In this work, various techniques have been explored for a better and improved causal network learning from data. Firstly, the problem of learning...
State-of-the-art personal robots need to perform complex manipulation tasks to be viable in complex scenarios. However, many of these robots, like the PR2, use manipulators with high degrees of freedom. High degrees of freedom are desirable from a functionality standpoint, but make the learning task more difficult by adding a...