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Filtering by: Funding statement Work described in this contribution was supported by the National Institutes of Health Grants R01AG025372, S10RR025628 and P30ES000210. YVV is supported by the National Science Foundation under Grant No. 0924027, the National Institutes of Health under Grant No. R01RR026275 and a grant from OSU RERF. Remove constraint Funding statement: Work described in this contribution was supported by the National Institutes of Health Grants R01AG025372, S10RR025628 and P30ES000210. YVV is supported by the National Science Foundation under Grant No. 0924027, the National Institutes of Health under Grant No. R01RR026275 and a grant from OSU RERF.

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  • MaierClaudiaChemistryProteinModificationElectrophilic.pdf

    Creator:
    Vasil'ev, Yury V., Tzeng, Shin-Chen, Huang, Lin, and Maier, Claudia S.
    Abstract:
    The post-translational modification of proteins by electrophilic oxylipids is emerging as an important mechanism that contributes to the complexity of proteomes. Enzymatic and non-enzymatic oxidation of biological lipids results in the formation of chemically diverse electrophilic carbonyl compounds, such as 2-alkenals and 4-hydroxy alkenals, epoxides and eicosanoids with reactive cyclopentenone...
    Full Text:
    the protein which is determined by the microenvironment which, in turn, affects the pKa of the