Adenovirus initiates strand-displacement DNA replication from
origins located in identical inverted terminal repetitions (ITRs).
Panhandle structures, formed by base-pairing between ITRs on the
displaced strands, have been proposed as replication intermediates for
complementary strand synthesis. Plasmid molecules containing a single
adenovirus terminal sequence and specially arranged inverted repeat
sequences were...
Inhaled and intranasal corticosteroids (ICS and INS) are among the mainstays of the treatment for asthma and allergic rhinitis, respectively, and also carry the potential to suppress the hypothalamic–pituitary–adrenal (HPA) axis. Several important factors affect the interpretability of trials investigating the impact of ICS and INS on the HPA axis....
Knowledge of the shear stress on a fault during slip is necessary
for a physically-based understanding of earthquakes. Borehole
temperature measurements inside the fault zone immediately after
an earthquake can record the energy dissipated by this stress. In the
first Wenchuan Earthquake Fault Zone Scientific Drilling Project
hole (Sichuan province,...