Polyhalogenated quinones are a class of carcinogenic intermediates. We found recently that the highly reactive and biologically/environmentally important center [dot]OH can be produced by polyhalogenated quinones and H₂O₂ independent of transition metal ions. However, it is not clear whether this unusual metal-independent center dot OH producing system can induce potent...
The design of a competition-winning aero package must consider multiple vehicle attitudes. Aerodynamic concepts simulated in heave, pitch, roll, high-speed yaw, and low-speed yaw to design a stable and predictable aero package. The methodology automates the simulation setup process of five vehicle attitudes. The overall and subsystem force coefficients are...
Dysferlin is a ∼230 kDa terminally anchored membrane protein that is ubiquitously expressed, but is particularly enriched in skeletal and cardiac muscle tissue. Mutations covering the length of the protein have been linked to muscle wasting diseases including limb-girdle muscular dystrophy and Myoshi myopathy. Dysferlin has been shown to play...
Cell migration is fundamental for physiological processes such as immune re-sponses, wound healing and development. It is also a critical characteristic of metastatic cancer cells. An extensive amount of studies have focused on 2D sub-strates in order to understand the mechanism of cancer metastasis. However, much less is known about...
Most tasks in natural language processing (NLP) involves structured information from both input (e.g., a sentence or a paragraph) and output (e.g., a tag sequence, a parse tree or a translated sentence). While neural models achieve great successes in other domains such as computer vision, applying those frameworks to NLP...
Most studies of plant disease epidemiology have focused on epidemics in host
populations composed of a single genotype. But crop plant diversity can be a useful
means of improving the deployment of resistance genes. In a series of experiments with wheat stripe rust and potato late blight, we studied factors...
Autonomous robotic agents are on their way to becoming in-home personal assistants, construction assistants, and warehouse workers. The degree of autonomy of such systems is reflected by the manner in which we specify goals to them; the abstraction of low-level commands to high-level goals goes hand-in-hand with increased autonomy. In...