Developing new medical tests and identifying single biomarkers or panels of biomarkers with superior accuracy over existing classifiers promotes lifelong health of individuals and populations. Before a medical test can be routinely used in clinical practice, its accuracy within diseased and non-diseased populations must be rigorously evaluated. We introduce a...
In diagnostic medicine, estimating the diagnostic accuracy of a group of raters or medical tests relative to the gold standard is often the primary goal. When a gold standard is absent, latent class models where the unknown gold standard test is treated as a latent variable are often used. However,...
Brucellosis is a disease of veterinary and public health importance worldwide. In sub-
Saharan Africa, where this disease has been detected in several free-ranging wildlife species,
successful disease control may be dependent on accurate detection in wildlife reservoirs,
including African buffalo (Syncerus caffer). This study estimates the sensitivity and specificity...
Full Text:
Evaluation of the SensitivityandSpecificity of an Enzyme
Brucellosis is a disease of veterinary and public health importance worldwide. In sub-
Saharan Africa, where this disease has been detected in several free-ranging wildlife species,
successful disease control may be dependent on accurate detection in wildlife reservoirs,
including African buffalo (Syncerus caffer). This study estimates the sensitivity and specificity...
Full Text:
distribution of each tests’ sensitivityandspecificity (ELISA, RBT, CFT). The data is 3
represented as a
Brucellosis is a disease of veterinary and public health importance worldwide. In sub-
Saharan Africa, where this disease has been detected in several free-ranging wildlife species,
successful disease control may be dependent on accurate detection in wildlife reservoirs,
including African buffalo (Syncerus caffer). This study estimates the sensitivity and specificity...