Primary Intestinal and Vertebral Chordomas in Laboratory Zebrafish (Danio rerio) Public Deposited

http://ir.library.oregonstate.edu/concern/articles/1v53jz82q

This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by the American College of Veterinary Pathologists and published by Sage Publications. It can be found at:  http://intl-vet.sagepub.com/.

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  • Chordomas are uncommon neoplasms arising from notochord remnants, most commonly occurring in the axial skeleton. Extraskeletal soft tissue chordomas are rare primary tumors, and primary intestinal chordomas have not been reported. Herein we report 24 cases of spontaneous primary intestinal chordomas in zebrafish, as well as 9 spontaneous vertebral chordomas. Both intestinal and vertebral tumors showed invasive behavior, although more commonly in the latter. In all cases of primary intestinal chordomas, there was no axial or peripheral skeletal or other non-visceral involvement. Although uncommon, intestinal chordomas represent a unique background lesion in aged zebrafish.
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  • Cooper, T. K., Murray, K. N., Spagnoli, S., & Spitsbergen, J. M. (2015). Primary Intestinal and Vertebral Chordomas in Laboratory Zebrafish (Danio rerio). Veterinary Pathology, 52(2), 388-392. doi:10.1177/0300985814537531
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  • description.provenance : Submitted by Erin Clark (erin.clark@oregonstate.edu) on 2014-12-29T19:31:22Z No. of bitstreams: 3 SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral.pdf: 341810 bytes, checksum: cfb4f4858fbde187445f93f1933357f7 (MD5) SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral_Figures1-6.jpg: 5300892 bytes, checksum: fbbc021dc531040b873f1f1685857cdb (MD5) SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral_FigureS1.jpg: 919764 bytes, checksum: 00cf01c2c650e5693f0b4db048c44400 (MD5)
  • description.provenance : Approved for entry into archive by Erin Clark(erin.clark@oregonstate.edu) on 2014-12-29T19:31:53Z (GMT) No. of bitstreams: 3 SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral.pdf: 341810 bytes, checksum: cfb4f4858fbde187445f93f1933357f7 (MD5) SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral_Figures1-6.jpg: 5300892 bytes, checksum: fbbc021dc531040b873f1f1685857cdb (MD5) SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral_FigureS1.jpg: 919764 bytes, checksum: 00cf01c2c650e5693f0b4db048c44400 (MD5)
  • description.provenance : Made available in DSpace on 2014-12-29T19:31:53Z (GMT). No. of bitstreams: 3 SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral.pdf: 341810 bytes, checksum: cfb4f4858fbde187445f93f1933357f7 (MD5) SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral_Figures1-6.jpg: 5300892 bytes, checksum: fbbc021dc531040b873f1f1685857cdb (MD5) SpitsbergenJanMicrobiologyPrimaryIntestinalVertebral_FigureS1.jpg: 919764 bytes, checksum: 00cf01c2c650e5693f0b4db048c44400 (MD5) Previous issue date: 2014-06-09

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