- Active-sampling approaches are commonly used for
personal monitoring, but are limited by energy usage and data that may
not represent an individual’s exposure or bioavailable concentrations.
Current passive techniques often involve extensive preparation, or are
developed for only a small number of targeted compounds. In this work,
we present a novel application for measuring bioavailable exposure with
silicone wristbands as personal passive samplers. Laboratory methodology
affecting precleaning, infusion, and extraction were developed
from commercially available silicone, and chromatographic background
interference was reduced after solvent cleanup with good extraction
efficiency (>96%). After finalizing laboratory methods, 49 compounds
were sequestered during an ambient deployment which encompassed a
diverse set of compounds including polycyclic aromatic hydrocarbons
(PAHs), consumer products, personal care products, pesticides,
phthalates, and other industrial compounds ranging in log K[subscript ow] from −0.07 (caffeine) to 9.49 (tris(2-ethylhexyl) phosphate).
In two hot asphalt occupational settings, silicone personal samplers sequestered 25 PAHs during 8- and 40-h exposures, as well as
2 oxygenated-PAHs (benzofluorenone and fluorenone) suggesting temporal sensitivity over a single work day or week (p < 0.05,
power =0.85). Additionally, the amount of PAH sequestered differed between worksites (p < 0.05, power = 0.99), suggesting
spatial sensitivity using this novel application.