Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression Public Deposited

http://ir.library.oregonstate.edu/concern/articles/6m311q95z

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  • As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks.
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  • Nahta, R., Al-Mulla, F., Al-Temaimi, R., Amedei , A., Andrade-Vieira, R., Bay, S. ... & Bisson, W. H. (2015). Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis, 36(Suppl 1), S2-18. doi: 10.1093/carcin/bgv028
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  • description.provenance : Made available in DSpace on 2015-07-15T17:41:49Z (GMT). No. of bitstreams: 1 BissonWilliamHEnvironmentalMolecularToxicologyMechanismsEnvironmentalChemicals.pdf: 4464398 bytes, checksum: 61a911970c47c406670f4b03e040116a (MD5) Previous issue date: 2015-06
  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2015-07-15T17:41:48Z (GMT) No. of bitstreams: 1 BissonWilliamHEnvironmentalMolecularToxicologyMechanismsEnvironmentalChemicals.pdf: 4464398 bytes, checksum: 61a911970c47c406670f4b03e040116a (MD5)
  • description.provenance : Submitted by Patricia Black (patricia.black@oregonstate.edu) on 2015-07-15T16:03:42Z No. of bitstreams: 1 BissonWilliamHEnvironmentalMolecularToxicologyMechanismsEnvironmentalChemicals.pdf: 4464398 bytes, checksum: 61a911970c47c406670f4b03e040116a (MD5)

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