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Citeable URL: http://ir.library.oregonstate.edu/concern/articles/6m311q95z

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Creator	Nahta, Rita Bisson, William H. Al-Temaimi, Rabeah Al-Mulla, Fahd et al.
Abstract or Summary	As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks.
Resource Type	Article
DOI	10.1093/carcin/bgv028
Date Available	2015-07-15T17:41:49+00:00
Date Issued	2015-06
Citation	Nahta, R., Al-Mulla, F., Al-Temaimi, R., Amedei , A., Andrade-Vieira, R., Bay, S. ... & Bisson, W. H. (2015). Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression. Carcinogenesis, 36(Suppl 1), S2-18. doi: 10.1093/carcin/bgv028
Series	Vol. 36 Suppl. 1 Carcinogenesis
Rights Statement	Copyright Not Evaluated
Funding Statement (additional comments about funding)	Winship Cancer Institute (R.N.); FONDECYT (#1120006), MINEDUC (G.M.C.); NIH/NCI (R01CA172392 to R.C.C.); American Cancer Society (116683-RSG-09-087-01-TBE to K.C.-S.); Canadian Breast Cancer Foundation and the Canadian Institute of Health Research (D.L., C.N.); Dalhousie Medical Research Foundation, Beatrice Hunter Cancer Research Institute (P.M.); Czech Science Foundation (13-07711S to J.V.); Fondazione Cariplo (2011-0370 to C.M.); Kuwait Institute for the Advancement of Sciences (2011-1302-06 to F. al-M.); Grant University Scheme (RUGs) Ministry of Education Malaysia (04-02-12-2099RU to R.A.H.); Italian Ministry of University and Research (2009FZZ4XM_002 to A.A); the University of Florence (ex60%2012 to A.A.); US Public Health Service Grants (RO1 CA92306, RO1 CA92306-S1, RO1 CA113447 to R.R.); Department of Science and Technology, Government of India (SR/FT/LS-063/2008 to N.S.); Osteopathic Heritage Foundation to G.S.G.
Publisher	Oxford University Press
Peer Reviewed	Yes
Language	English [eng]
Replaces	http://hdl.handle.net/1957/56436
Additional Information	description.provenance : Submitted by Patricia Black (patricia.black@oregonstate.edu) on 2015-07-15T16:03:42Z No. of bitstreams: 1 BissonWilliamHEnvironmentalMolecularToxicologyMechanismsEnvironmentalChemicals.pdf: 4464398 bytes, checksum: 61a911970c47c406670f4b03e040116a (MD5) description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2015-07-15T17:41:48Z (GMT) No. of bitstreams: 1 BissonWilliamHEnvironmentalMolecularToxicologyMechanismsEnvironmentalChemicals.pdf: 4464398 bytes, checksum: 61a911970c47c406670f4b03e040116a (MD5) description.provenance : Made available in DSpace on 2015-07-15T17:41:49Z (GMT). No. of bitstreams: 1 BissonWilliamHEnvironmentalMolecularToxicologyMechanismsEnvironmentalChemicals.pdf: 4464398 bytes, checksum: 61a911970c47c406670f4b03e040116a (MD5) Previous issue date: 2015-06

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