Article

 

Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression Pubblico Deposited

Contenuto scaricabile

Scarica il pdf
https://ir.library.oregonstate.edu/concern/articles/6m311q95z

Descriptions

Attribute NameValues
Creator
Abstract
  • As part of the Halifax Project, this review brings attention to the potential effects of environmental chemicals on important molecular and cellular regulators of the cancer hallmark of evading growth suppression. Specifically, we review the mechanisms by which cancer cells escape the growth-inhibitory signals of p53, retinoblastoma protein, transforming growth factor-beta, gap junctions and contact inhibition. We discuss the effects of selected environmental chemicals on these mechanisms of growth inhibition and cross-reference the effects of these chemicals in other classical cancer hallmarks.
  • This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by Oxford University Press. The published article can be found at: http://carcin.oxfordjournals.org/. The publisher and the author(s) have made this article open access.
Resource Type
DOI
Date Available
Date Issued
Citation
  • Rita Nahta, Fahd Al-Mulla, Rabeah Al-Temaimi, Amedeo Amedei, Rafaela Andrade-Vieira, Sarah N. Bay, Dustin G. Brown, Gloria M. Calaf, Robert C. Castellino, Karine A. Cohen-Solal, Anna Maria Colacci, Nichola Cruickshanks, Paul Dent, Riccardo Di Fiore, Stefano Forte, Gary S. Goldberg, Roslida A. Hamid, Harini Krishnan, Dale W. Laird, Ahmed Lasfar, Paola A. Marignani, Lorenzo Memeo, Chiara Mondello, Christian C. Naus, Richard Ponce-Cusi, Jayadev Raju, Debasish Roy, Rabindra Roy, Elizabeth P. Ryan, Hosni K. Salem, A.Ivana Scovassi, Neetu Singh, Monica Vaccari, Renza Vento, Jan Vondráček, Mark Wade, Jordan Woodrick, William H. Bisson; Mechanisms of environmental chemicals that enable the cancer hallmark of evasion of growth suppression, Carcinogenesis, Volume 36, Issue Suppl_1, 1 June 2015, Pages S2–S18, https://doi.org/10.1093/carcin/bgv028
Journal Title
Journal Volume
  • 36
Journal Issue/Number
  • Supp. 1
Academic Affiliation
Dichiarazione dei diritti
Funding Statement (additional comments about funding)
  • Winship Cancer Institute (R.N.); FONDECYT (#1120006), MINEDUC (G.M.C.); NIH/NCI (R01CA172392 to R.C.C.); American Cancer Society (116683-RSG-09-087-01-TBE to K.C.-S.); Canadian Breast Cancer Foundation and the Canadian Institute of Health Research (D.L., C.N.); Dalhousie Medical Research Foundation, Beatrice Hunter Cancer Research Institute (P.M.); Czech Science Foundation (13-07711S to J.V.); Fondazione Cariplo (2011-0370 to C.M.); Kuwait Institute for the Advancement of Sciences (2011-1302-06 to F. al-M.); Grant University Scheme (RUGs) Ministry of Education Malaysia (04-02-12-2099RU to R.A.H.); Italian Ministry of University and Research (2009FZZ4XM_002 to A.A); the University of Florence (ex60%2012 to A.A.); US Public Health Service Grants (RO1 CA92306, RO1 CA92306-S1, RO1 CA113447 to R.R.); Department of Science and Technology, Government of India (SR/FT/LS-063/2008 to N.S.); Osteopathic Heritage Foundation to G.S.G..
Publisher
Peer Reviewed
Language
Replaces

Le relazioni

Parents:

This work has no parents.

Elementi