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The Gene Ontology in 2010: extensions and refinements

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https://ir.library.oregonstate.edu/concern/articles/wp988k52z

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  • The Gene Ontology (GO) Consortium (http://www.geneontology.org) (GOC) continues to develop, maintain and use a set of structured, controlled vocabularies for the annotation of genes, gene products and sequences. The GO ontologies are expanding both in content and in structure. Several new relationship types have been introduced and used, along with existing relationships, to create links between and within the GO domains. These improve the representation of biology, facilitate querying, and allow GO developers to systematically check for and correct inconsistencies within the GO. Gene product annotation using GO continues to increase both in the number of total annotations and in species coverage. GO tools, such as OBO-Edit, an ontology-editing tool, and AmiGO, the GOC ontology browser, have seen major improvements in functionality, speed and ease of use.
  • This is the publisher’s final pdf. The published article is copyrighted by the author(s) and published by Oxford University Press. The published article can be found at: http://nar.oxfordjournals.org/.
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  • Gene Ontology Consortium. (2010). The Gene Ontology in 2010: extensions and refinements. Nucleic Acids Research, 38, D331-D335. doi:10.1093/nar/gkp1018
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  • 38
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  • National Human Genome Research Institute (NHGRI)(P41 HG02273 to GO PIs J.A.B., M.A., J.M.C., S.L.); GO Consortium member databases receive funding from several National Institutes of Health Institutes [National Human Genome Research Institute (HG000330 to M.G.D., HG02223 to Wormbase, HG004341 to K.E., HG003751 to Reactome, HG01315 to S.G.D., HG002659 to Z.F.I.N.); National Heart, Blood and Lung Institute (HL64541 to R.G.D.), National Institute of General Medical Sciences (U24GM077905, U24GM088849 to EcoliWiki)]; National Science Foundation (DBI#0703908 to Gramene, DBI#0417062 to TAIR, EF-0523736 to PAMGO); UK Medical Research Council (G0500293 to FlyBase); British Heart Foundation (SP/07/007/23671); European Union Sixth Framework Programme (LSHG-CT-2003-503269 to Reactome). Funding for open access charge: National Human Genome Research Institute (grant #P41HG02273).
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