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https://ir.library.oregonstate.edu/concern/articles/xg94hr38f

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  • Phytophthora pathogens secrete an array of specific effector proteins to manipulate host innate immunity to promote pathogen colonization. However, little is known about the host targets of effectors and the specific mechanisms by which effectors increase susceptibility. Here we report that the soybean pathogen Phytophthora sojae uses an essential effector PsAvh262 to stabilize endoplasmic reticulum (ER)-luminal binding immunoglobulin proteins (BiPs), which act as negative regulators of plant resistance to Phytophthora. By stabilizing BiPs, PsAvh262 suppresses ER stress-triggered cell death and facilitates Phytophthora infection. The direct targeting of ER stress regulators may represent a common mechanism of host manipulation by microbes.
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  • description.provenance : Made available in DSpace on 2016-06-27T21:30:30Z (GMT). No. of bitstreams: 3 krauserp1814662988.zip: 8403365 bytes, checksum: c7d134f4499912a7ca4eadeb597507fc (MD5) JingPhytophthoraSojaeEffector.pdf: 2884379 bytes, checksum: 2a91cce488a54c5bf6b5ffe70dc2734d (MD5) JingPhytophthoraSojaeEffectorSuppFigures1-14andTables1-2.pdf: 6399415 bytes, checksum: 0766c76e34b2e23b8a9d29727f433104 (MD5) Previous issue date: 2016-06
  • description.provenance : Approved for entry into archive by Patricia Black(patricia.black@oregonstate.edu) on 2016-06-27T21:30:30Z (GMT) No. of bitstreams: 3 krauserp1814662988.zip: 8403365 bytes, checksum: c7d134f4499912a7ca4eadeb597507fc (MD5) JingPhytophthoraSojaeEffector.pdf: 2884379 bytes, checksum: 2a91cce488a54c5bf6b5ffe70dc2734d (MD5) JingPhytophthoraSojaeEffectorSuppFigures1-14andTables1-2.pdf: 6399415 bytes, checksum: 0766c76e34b2e23b8a9d29727f433104 (MD5)
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