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Variation in Antibiotic Susceptibility of Uropathogens by Age among Ambulatory Pediatric Patients Public Deposited

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  • We compared uropathogen antibiotic susceptibility across age groups of ambulatory pediatric patients. For Escherichia coli (n=5,099) and other Gram-negative rods (n=626), significant differences (p<0.05) existed across age groups for ampicillin, cefazolin, and trimethoprim/sulfamethoxazole susceptibility. In E. coli, differences in trimethoprim/sulfamethoxazole susceptibility varied from 79% in children under 2 to 88% in ages 16-18 (p<0.001) while ampicillin susceptibility varied from 30% in children under 2 to 53% in ages 2-5 (p=0.015). Uropathogen susceptibility to common urinary anti-infectives may be lower in the youngest children. Further investigation into these differences is needed to facilitate appropriate and prudent treatment of urinary tract infections.
  • This is an author's peer-reviewed final manuscript, as accepted by the publisher. The published article is copyrighted by Elsevier and can be found at: http://www.sciencedirect.com/science/journal/08825963.
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  • McGregor, J. C., Quach, Y., Bearden, D. T., Smith, D. H., Sharp, S. E., & Guzman-Cottrill, J. A. (2014). Variation in Antibiotic Susceptibility of Uropathogens by Age Among Ambulatory Pediatric Patients. Journal of Pediatric Nursing, 29(2), 152-157. doi:10.1016/j.pedn.2013.09.001
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  • 29
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  • 2
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  • This study was supported by grants from the National Institutes of Health(KL2RR024141 to J.C.M.) and the American Association of Colleges of Pharmacy (NewInvestigator Program award to J.C.M.).
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  • description.provenance : Made available in DSpace on 2014-07-02T21:24:07Z (GMT). No. of bitstreams: 1McGregorJessinaPharmacyVariationAntibioticSusceptibility.pdf: 392988 bytes, checksum: 540988e388f08cd78834a4fc63b8bd9b (MD5) Previous issue date: 2014-03
  • description.provenance : Approved for entry into archive by Erin Clark(erin.clark@oregonstate.edu) on 2014-07-02T21:24:07Z (GMT) No. of bitstreams: 1McGregorJessinaPharmacyVariationAntibioticSusceptibility.pdf: 392988 bytes, checksum: 540988e388f08cd78834a4fc63b8bd9b (MD5)
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