There are a range of smaller-scale fish farms operating in Ghana producing mainly tilapia and catfish based on extensive (stocking of small reserviours), intensive and semi-intensive (earthen ponds & tanks) techniques. Aquaculture production in Ghana plays a significant role in the economic development of livelihoods of fish farmers and contributes significantly to the country’s Gross Domestic Pproduct (GDP). Production increased from 10,200mt (2010) to 44,610mt (2015). Production of fish is faced with many challenges. Some of these are related to availability, accessibility and price of feed, quality, quantity and price of seed, training of fish farmers, disease and water quality among others. This paper therefore examines the technical efficiency of its operators. Primary data collection was undertaken using semi-structured questionnaire transferred unto KoBo Toolbox on a phone tablet. The study sampled 346 fish farmers across the country. Method employed in sampling were stratification and multistage simple random sampling. SPSS and STATA were employed in analysis. Regression analysis employed Cob-Douglas Production Stochastic Frontier model. A total of 323 males (93.4%) and 23 females (6.6%) were sample for the study. Production system undertaken in the country are intensive, semi-intensive and extensive with most respondents undergoing semi-intensive system of production (72.5%). The mean technical efficiency of pond and tank fish farmers is estimated to be 70%. It implies that the pond and tank fish farmers are operating 30% below the production frontier given level of technology and it’s quite significant. Age of fish farmer, household size are significant determinants of technical efficiency.