The purse seine fishery that falls within the Western and Central Pacific Fisheries Commission Convention Area (WCPFC-CA) is one of the world’s most valuable fisheries with the value of catch averaging ($US3.3 billion between 2012 and 2016). In 2015 the WCPFC agreed to an interim target reference point (TRP) for skipjack (50%SBF=0) the dominant species in the purse seine fishery catch. In 2016 the WPCFC accepted a suggested initial list of performance indicators for tropical purse-seine fisheries for the purpose of the evaluation of harvest control rules. A number of economic measures, including “Maximising economic yield from the fishery”, were part of this list. This study examines the potential economic performance of the purse seine fishery under the nominated skipjack TRP and other skipjack stock levels using a regional bioeconomic model of the fishery. Influences on economic performance, at both a given level of stock and between different stock levels, of fluctuations in prices and costs, price responses to changes in catch levels and catch rates responses to changes in stock levels are examined.