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Understanding Statin Use in America and Gaps in Patient Education (USAGE): An Internet-Based Survey of 10,138 Current and Former Statin Users

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https://ir.library.oregonstate.edu/concern/articles/9z903081w

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  • Background: Statins substantially reduce cardiovascular disease risk and are generally well-tolerated, but many patients discontinue therapy. A better understanding of the characteristics of current and former statin users may be helpful for formulating strategies to improve long-term adherence. Objective: The Understanding Statin Use in America and Gaps in Education (USAGE) survey assessed the attitudes, beliefs, practices, and behavior of current and former statin users. Methods: Individuals ≥18 years who reported current or former statin use were identified within a registered consumer panel cohort in the United States and invited to participate in an Internet survey. Results: Of the 10,138 respondents, 8918 (88%) were current statin users and 1220 (12%) were former users. Participants (mean age 61 years) were predominantly Caucasian (92%), female (61%), middle income (median $44,504/yr), and had health insurance (93%). Among current users, 95% took a statin alone (the majority generic) and 70% had not missed a dose in the past month. Although ~70% reported that their physicians had explained the importance of cholesterol levels and danger to their heart, former users were less satisfied with the discussions (65% vs. 83%, p<0.05). Muscle-related side effects were reported by 69% and 25% of former and current users, respectively (p<0.05). The primary reason for discontinuation by former users was side effects (62%), and the primary reason for switching by current users was cost (32%). Conclusions: This survey provides important insights into behavior and attitudes among current and former statin users and the results suggest that more effective dialogue between healthcare providers and patients may increase persistence of statin use, particularly when the patient has concerns about drug costs and side effects.
  • Keywords: survey, statins, adherence, compliance, Internet, persistence
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  • Jerome D. Cohen, Eliot A. Brinton, Matthew K. Ito, and Terry A. Jacobson. Understanding Statin Use in America and Gaps in Patient Education (USAGE): An internet-based survey of 10,138 current and former statin users. Journal of Clinical Lipidology, 1 May 2012 (volume 6 issue 3, Pages 208-215, DOI: 10.1016/j.jacl.2012.03.003).
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  • 6
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  • 3
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  • This study was funded by Kowa Pharmaceuticals America, Inc. (Montgomery, AL), Eli Lilly and Company (Indianapolis, IN), and the National Lipid Association (Jacksonville, FL).
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