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https://ir.library.oregonstate.edu/concern/defaults/fq977v61w

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  • Context: Antibiotic prescribing in hospice patients is complicated by the focus on palliative rather than curative care and concerns regarding increasing antibiotic resistance. Objective: To estimate antibiotic use in a national sample of hospice patients and identify facility and patient characteristics associated with antibiotic use in this population. Methods: This was an analysis of data from the 2007 National Home and Hospice Care Survey, a nationally-representative sample of U.S. hospice agencies. We included data from 3,884 patients who died in hospice care. Our primary outcome measure was prevalence of antibiotic use in the last 7 days of life. Diagnoses, including potential infectious indications for antibiotic use, were defined using International Classification of Diseases, Ninth Revision (ICD-9) codes. Chi-square tests and t-tests were used to quantify associations of patient and facility characteristics with antibiotic use. Results: During the last 7 days of life, 27% (95% confidence interval (CI); 24%, 30%) of patients received at least one antibiotic and 1.3% (95% CI; 0.7%, 2.0%) received ≥ 3 antibiotics. Among patients who received at least one antibiotic, 15% (95% CI; 10%, 20%) had a documented infectious diagnosis, compared with 9% (95% CI; 7%, 11%) who had an infectious diagnosis but received no antibiotics. Conclusions: In this nationally-representative sample, 27% of hospice patients received an antibiotic during the last 7 days of life, most without a documented infectious diagnosis. Further research is needed to elucidate the role of antibiotics in this patient population to maintain palliative care goals while reducing unnecessary antibiotic use.
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  • description.provenance : Submitted by Deanne Bruner (deanne.bruner@oregonstate.edu) on 2013-12-12T00:20:15Z No. of bitstreams: 1 FurunoJonPharmacyNationwideAnalysisAntibiotic.pdf: 429696 bytes, checksum: 82150a4796541bc98a72796151799d43 (MD5)
  • description.provenance : Made available in DSpace on 2013-12-12T00:25:13Z (GMT). No. of bitstreams: 1 FurunoJonPharmacyNationwideAnalysisAntibiotic.pdf: 429696 bytes, checksum: 82150a4796541bc98a72796151799d43 (MD5) Previous issue date: 2013-10
  • description.provenance : Approved for entry into archive by Deanne Bruner(deanne.bruner@oregonstate.edu) on 2013-12-12T00:25:13Z (GMT) No. of bitstreams: 1 FurunoJonPharmacyNationwideAnalysisAntibiotic.pdf: 429696 bytes, checksum: 82150a4796541bc98a72796151799d43 (MD5)

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