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Using 4-D imaging of the zebrafish model to observe pharmacodynamics of a therapeutic drug on glioblastoma Public Deposited

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  • Glioblastoma Multiform • Type of aggressive brain cancer • Five year survival rate of 4.70% • Not often detected until it’s in the later stages when the symptoms appear • Surgery is not an effective option due to invasion and proliferation of glioblastoma cells outside of the tumor mass before and after surgery Why the Zebrafish Model? • Transparent body • Organism size • Short assay period • Little media required • No adaptive immune system for 28 dpf • Vertebrate anatomy and brain microenvironment
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  • SURE Science Scholarship. Award number 1337774 from the National Science Foundation, MRI: Acquisition of Confocal and Two-Photon Excitation Microscope.
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