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Spectroscopic and Structural Characterization of Farnesoid X Receptor Agonists and Antagonists Public Deposited

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  • Farensoid X Receptor (FXR) is a very flavoring protein for the treatment and prevention of the many conditions related to metabolic syndrome. Our experiment explores the binding activities of FXR when introduced to various natural and synthetic ligands. Currently, an initial assay showing the Stern-Volmer relationship of our date supports our prediction that agonist and antagonist ligands display different binding behaviors when exposed to FXR. However, additional experiments are needed in order to fully establish and refine our developing assay.
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  • The Howard Hughes Medical Institute; Undergraduate Research, Innovation, Scholarship Creativity (URISC); Ray, Frances, and Dale Cripps Student Support Fund scholarships
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  • description.provenance : Submitted by Xiao Chang (changx@onid.orst.edu) on 2013-06-05T09:27:41Z No. of bitstreams: 3 Chang.Xiao HHMI 2012 Presentation.pdf: 283220 bytes, checksum: ea9bb2daa9c44c80e2db240b5b8119fc (MD5) Chang.Xiao HHMI 2012 Presentation.pptx: 22276025 bytes, checksum: 5ab4b45d5d1857bbe9c87b414108e847 (MD5) Xiao Lan Chang at HHMI 2012.mp4: 26690105 bytes, checksum: 1956cbd00a7d330ae06e0e7224da0066 (MD5)
  • description.provenance : Made available in DSpace on 2013-06-05T18:11:11Z (GMT). No. of bitstreams: 3 Chang.Xiao HHMI 2012 Presentation.pdf: 283220 bytes, checksum: ea9bb2daa9c44c80e2db240b5b8119fc (MD5) Chang.Xiao HHMI 2012 Presentation.pptx: 22276025 bytes, checksum: 5ab4b45d5d1857bbe9c87b414108e847 (MD5) Xiao Lan Chang at HHMI 2012.mp4: 26690105 bytes, checksum: 1956cbd00a7d330ae06e0e7224da0066 (MD5)
  • description.provenance : Approved for entry into archive by Deanne Bruner(deanne.bruner@oregonstate.edu) on 2013-06-05T18:11:11Z (GMT) No. of bitstreams: 3 Chang.Xiao HHMI 2012 Presentation.pdf: 283220 bytes, checksum: ea9bb2daa9c44c80e2db240b5b8119fc (MD5) Chang.Xiao HHMI 2012 Presentation.pptx: 22276025 bytes, checksum: 5ab4b45d5d1857bbe9c87b414108e847 (MD5) Xiao Lan Chang at HHMI 2012.mp4: 26690105 bytes, checksum: 1956cbd00a7d330ae06e0e7224da0066 (MD5)

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