Graduate Project

 

Design and Implementation of an Alternating Current Susceptometer for Measuring Brownian Relaxation Time of Magnetic Nanoparticles Suspended in a Liquid Medium Public Deposited

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https://ir.library.oregonstate.edu/concern/graduate_projects/rr172296x

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  • In this work, an alternating current (ac) magnetic susceptometer is designed and implemented to track the Brownian relaxation time of magnetic nanoparticles that are suspended in a liquid medium. The detection technique based on the Brownian relaxation time of magnetic nanoparticles has found its way in a variety of biosensing applications ranging from the detection of biochemical binding to blood clotting. One of the ways to detect the change in the viscosity of blood, in the clotting process, is to track the change in the Brownian relaxation time of magnetic nanoparticles, delivered in blood, as a tracer. This project uses the frequency response of the ac magnetic susceptibility of the magnetic nanoparticles, suspended in a liquid medium, to track the Brownian relaxation time of the nanoparticles in that specific medium. The implemented ac susceptometer is capable of tracking a relaxation time between 1 ms and 10 µs. For a tracer nanoparticle with a hydrodynamic diameter of 20 nm, the detection range of the implemented ac susceptometer covers a viscosity window between 0.52 mPa.s and 52 mPa.s. Most of the traditional practices use the movement of the detection setup to cancel the inductive feed through. Unlike the traditional practices, an active cancellation technique is employed in the implemented susceptometer to stretch the lower limit of the measurement down to 50 nAm2 ac magnetic moment, across the frequency range from 1 kHz to 100 kHz.
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  • description.provenance : Approved for entry into archive by Steven Van Tuyl(steve.vantuyl@oregonstate.edu) on 2017-08-01T23:35:13Z (GMT) No. of bitstreams: 1Paul, Partha Sarathi (2017-06-27).pdf: 882932 bytes, checksum: 716be9894fb19f6ec08be77345f0f6a5 (MD5)
  • description.provenance : Made available in DSpace on 2017-08-01T23:35:13Z (GMT). No. of bitstreams: 1Paul, Partha Sarathi (2017-06-27).pdf: 882932 bytes, checksum: 716be9894fb19f6ec08be77345f0f6a5 (MD5)
  • description.provenance : Submitted by Partha Sarathi Paul (paulp@oregonstate.edu) on 2017-07-27T22:03:09ZNo. of bitstreams: 1Paul, Partha Sarathi (2017-06-27).pdf: 882932 bytes, checksum: 716be9894fb19f6ec08be77345f0f6a5 (MD5)

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