A Ross-Macdonald Model with Vector Demography Public Deposited

http://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/0r967904f

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  • Malaria is a vector-borne disease that has affected humans and other animals for a long time and which has shown high prevalence among different populations. During the beginning of the 20th century, Sir Ronald Ross and George Macdonald developed a model that represents the spread of malaria through the interaction of human and mosquito populations. Throughout this work, we study the vector-host dynamics of Malaria with respect to a model based on the work of Ross and Macdonald, which includes the demography of susceptible mosquitoes. With the help of both classic and modern techniques of dynamical systems, we analyze the different characteristics of the proposed model and its connection to corresponding biological scenarios. Some features of this model are the existence of a unique endemic equilibrium if the basic reproduction number is larger than 1; the global asymptotic stability of this equilibrium, provided a sector condition for the function describing the vector demography holds; and the persistence of Malaria when the basic reproduction number is larger than 1. It is also shown that the endemic equilibrium can be unstable under certain condition.
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