Comparison of a Persistent Random Walk to 3D Chemo taxis in MDA-MB-231 Cancer Cells Public Deposited

http://ir.library.oregonstate.edu/concern/undergraduate_thesis_or_projects/37720f122

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  • This research specifically examines the collective motion of populations of MDA-MB-231 breast cancer cells under the influence of a chemo-attractant gradient. Their motion is compared to the mathematical model of a persistent random walk, measuring the persistence bias of the cells from their autocorrelation function and applying to the mean squared distribution function predicted by the persistent random walk model. The motion of cells within the population is also analyzed; comparing free and caged cancer cell motion to the model of a persistent random walk. The results show strong evidence towards the conclusion that the collective motion of breast cancer cells does not fit into the model of a persistent random walk.
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  • description.provenance : Made available in DSpace on 2015-06-09T13:24:46Z (GMT). No. of bitstreams: 1Thayer-FreemanCameron2015.pdf: 1099017 bytes, checksum: f6a57cd6e67462c41df5c20f26cc0221 (MD5) Previous issue date: 2015-06-08
  • description.provenance : Submitted by Cameron Thayer-Freeman (thayerfc@onid.orst.edu) on 2015-06-08T21:13:53ZNo. of bitstreams: 1Thayer-FreemanCameron2015.pdf: 1099017 bytes, checksum: f6a57cd6e67462c41df5c20f26cc0221 (MD5)
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