Graduate Thesis Or Dissertation

 

Clearance of plasma cortisol in coho salmon, Oncorhynchus kisutch, at various stages of smoltification Public Deposited

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  • The metabolic clearance rate (MCR) of plasma radioactivity after a single intracardial injection of ³H-cortisol was elevated during the Spring in yearling coho salmon, Oncorhynchus kisutch. The reasons for this increase in MCR are not clear, but graphical analysis suggested that there may be a seasonal correlation between MCR and gill Na/K-ATPase activity. The main plasma metabolite of ³H-cortisol was ³H-cortisone, and it appeared very rapidly following injection of the original radiotracer. The stress of handling as used in the injection protocol and various anesthetic treatments did not affect clearance of cortisol from plasma.
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