Low-Dose Ionizing Radiation Solid Cancer Risk in Adults: Radiation Hormesis Study Design Public Deposited

http://ir.library.oregonstate.edu/concern/graduate_thesis_or_dissertations/5138jm08b

Descriptions

Attribute NameValues
Creator
Abstract or Summary
  • Cancer risk at low-dose ionizing radiation has been the subject of great scientific controversy in the past century. The clear majority of national and international radiation protection regulators adopt the linear no-threshold (LNT) model based on the atomic-bomb survivors Life Span Study (LSS) for solid cancer risk assessment. The LNT model assumes a linear relationship between radiation dose and cancer risk including interpolation of high dose values down to zero dose with no ‘safe’ threshold. New scientific evidence in the fields of molecular biology and epidemiology challenge the validity of the LNT model suggesting beneficial effects at low doses of ionizing radiation in a process better known as ‘hormesis’. This paper investigates current evidence for radiation hormesis with respect to solid cancer risks in adults and proposes a modest study design to test the hormesis hypothesis in humans with the potential of using low dose ionizing radiation to reduce solid cancer incidence in a population, if hormesis is proven. Current evidence confirms that hormesis does occur at low dose and low dose rates of low LET ionizing radiation. Every effort should be made from scientists in related fields in order to make the best use of the hormesis phenomenon with the aim of benefiting and protecting the public as the main objectives.
Resource Type
Date Available
Date Issued
Degree Level
Degree Name
Degree Field
Degree Grantor
Commencement Year
Advisor
Committee Member
Academic Affiliation
Non-Academic Affiliation
Rights Statement
Peer Reviewed
Language
Replaces
Additional Information
  • description.provenance : Made available in DSpace on 2017-09-20T22:41:02Z (GMT). No. of bitstreams: 1AlhussanAbdulazizS2017.pdf: 1519328 bytes, checksum: 114cbe645dd095e1e0dbbb5b922e23e0 (MD5) Previous issue date: 2017-09-01
  • description.provenance : Submitted by Abdulaziz Alhussan (alhussaa@oregonstate.edu) on 2017-09-07T23:42:33ZNo. of bitstreams: 1AlhussanAbdulazizS2017.pdf: 1519328 bytes, checksum: 114cbe645dd095e1e0dbbb5b922e23e0 (MD5)
  • description.provenance : Approved for entry into archive by Julie Kurtz(julie.kurtz@oregonstate.edu) on 2017-09-08T17:33:44Z (GMT) No. of bitstreams: 1AlhussanAbdulazizS2017.pdf: 1519328 bytes, checksum: 114cbe645dd095e1e0dbbb5b922e23e0 (MD5)
  • description.provenance : Approved for entry into archive by Steven Van Tuyl(steve.vantuyl@oregonstate.edu) on 2017-09-20T22:41:02Z (GMT) No. of bitstreams: 1AlhussanAbdulazizS2017.pdf: 1519328 bytes, checksum: 114cbe645dd095e1e0dbbb5b922e23e0 (MD5)

Relationships

In Administrative Set:
Last modified: 02/12/2018

Downloadable Content

Download PDF
Citations:

EndNote | Zotero | Mendeley

Items